Quantitative Evaluation of the Real-World Harmonization Status of Laboratory Test Items Using External Quality Assessment Data.

Background: In recent decades, the analytical quality of clinical laboratory results has substantially increased because of collaborative efforts. To effectively utilize laboratory results in applications, such as machine learning through big data, understanding the level of harmonization for each test would be beneficial. We aimed to develop a quantitative harmonization index that reflects the harmonization status of real-world laboratory tests.

Preoperative prediction of metastatic pheochromocytoma and paraganglioma using clinical, genetic, and biochemical markers: A cohort study.

Background: The prevalence of metastatic pheochromocytoma and paraganglioma (PPGL) is approximately 15%-20%. Although there are indicators to assess metastatic risks, none of them predict metastasis reliably. Therefore, we aimed to develop and validate a scoring system using clinical, genetic, and biochemical risk factors to preoperatively predict the metastatic risk of PPGL.

Impact of Academia-Government Collaboration on Laboratory Medicine Standardization in South Korea: analysis of eight years creatinine proficiency testing experience.

Objectives: To evaluate the performance of the Academia-Government Collaboration for Laboratory Medicine Standardization in Korea (KR-STDZN) based on data from KR-STDZN proficiency testing (KR-STDZN-PT) for creatinine over eight years (2015-2022).

Methods: We used KR-STDZN-PT data of creatinine tests from 2015 to 2022. Acceptance of the participating institutions' test results was assessed by calculating the acceptance performance as absolute bias (absBias%), total coefficient of variance (tCV%), and total error (TE%) for each sample using six measurements from each institution and true values of each reference material.

Design optimization and implementation of a Fourier transform spectrometer with rotating motion for 0.1 cm resolution spectroscopy.

In this paper, we present the design optimization and implementation of a high-resolution near-infrared Fourier transform spectrometer (FTS) based on a rotating motion. The FTS system incorporates a rotating mirror-pair for scanning the optical path length (OPL). The design optimization process is performed to maximize the scanning range to obtain a resolution of 0.

Strategies to shorten turnaround time in outpatient laboratory.

Background: Turnaround time (TAT) is one of the most important indicators of laboratory quality. For the outpatient routine chemistry tests whose results are checked by clinicians on the same day, we set a quality goal that >90% of these samples should be reported within 60 min. As more than 20% of the samples failed to achieve this goal in 2020, we introduced an additional autoanalyzer and a real-time monitoring system to improve this rate.

The biasing effects of selection and attrition on estimating the mean.

Organizational and validation researchers often work with data that has been subjected to selection on the predictor and attrition on the criterion. These researchers often use the data observed under these conditions to estimate either the predictor or criterion's restricted population means. We show that the restricted means due to direct or indirect selection are a function of the population means plus the selection ratios.

First case report of Solobacterium moorei bacteremia due to acute cholangitis in South Korea.

Solobacterium moorei is an anaerobic gram-positive bacillus that rarely causes bacteremia. Herein, we report a case of S. moorei bacteremia associated with acute cholangitis in a patient without malignancy.

The problem of measurement bias in comparing selected subgroups.

Estimates of subgroup differences are routinely used as part of a comprehensive validation system, and these estimates serve a critical role, including evaluating adverse impact. Unfortunately, under direct range restriction, a selected mean ( ) is a biased estimator of the population mean as well as the selected true score mean . This is due partly to measurement bias.

The Prevalence of Metabolic Syndrome and Its Related Risk Complications among Koreans.

There is an increasing number of metabolic syndrome (MetS) patients worldwide, and there is no exception in South Korea. The risk complications of metabolic syndrome have been investigated by many previous research studies, while no data on any current trends of MetS are available. Therefore, the present study investigates the recent prevalence of MetS and its associated risk complications in Korean adults by using the Korean National Health and Nutrition Examination Survey (KNHANES).

A novel hinged ankle foot orthosis for gait performance in chronic hemiplegic stroke survivors: a feasibility study.

Stroke survivors with gait disturbances may use ankle foot orthoses (AFOs). However, most AFOs come in one-piece styles, which make it difficult for spasticity-affected stroke survivors to don. AFOs are also limited since they do not properly prevent ankle joint for foot drop by itself.

Usability of the Thera-Band® to improve foot drop in stroke survivors.

Background: Stroke survivors show "foot drop", dragging their toes on the ground in the swing phase of gait. Ineffective ankle dorsiflexion may result in an abnormal gait pattern.

Objective: The purpose of this study was to investigate the effect of ankle Thera-Band® use on gait patterns in stroke survivors.