Total synthesis of (-)-flueggenine A and (-)-15'--flueggenine D.

Securinega alkaloids, known for their unique structures and neuroplasticity-inducing potential, are promising candidates for treating neurodegenerative diseases such as depression and substance use disorders (SUD). Herein, we delineate the total synthesis of two dimeric Rauhut-Currier (RC) reaction-based securinega alkaloids, (-)-flueggenine A and (-)-15'--flueggenine D. The key step involved a novel reductive Heck dimerization strategy, utilizing a silyl-tethered enone coupling partner to ensure the desired reactivity and stereoselectivity.

SAR ATR for Limited Training Data Using DS-AE Network.

Although automatic target recognition (ATR) with synthetic aperture radar (SAR) images has been one of the most important research topics, there is an inherent problem of performance degradation when the number of labeled SAR target images for training a classifier is limited. To address this problem, this article proposes a double squeeze-adaptive excitation (DS-AE) network where new channel attention modules are inserted into the convolutional neural network (CNN) with a modified ResNet18 architecture. Based on the squeeze-excitation (SE) network that employs a representative channel attention mechanism, the squeeze operation of the DS-AE network is carried out by additional fully connected layers to prevent drastic loss in the original channel information.