Publications by authors named "Seung June Oh"

Objective: This study evaluates surgical outcomes in benign prostatic hyperplasia (BPH) patients undergoing transurethral enucleation using various holmium laser (HoLEP) settings and/or bipolar devices (BipoLEP).

Design: This study was retrospective.

Methods: We retrospectively analyzed 158 BPH patients treated surgically, categorized by method: BipoLEP ( = 28), HoLEP with short pulse (HoLEP-SP,  = 26), HoLEP with long pulse and low energy (HoLEP-LP/LE,  = 29), HoLEP with long pulse and high energy (HoLEP-LP/HE,  = 26), HoLEP using Moses technology (HoLEP-Mo,  = 19), and a combination of HoLEP and BipoLEP (HoLEP-mix,  = 30).

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Article Synopsis
  • The study investigates how the distance between the laser fiber tip and soft tissue affects the destruction of that tissue during holmium laser enucleation of the prostate (HoLEP).
  • By experimenting with a soft tissue phantom at various distances, the researchers evaluated the effects of laser pulses on tissue destruction and thermal impact.
  • Results show that as the distance increases, the laser's ability to destroy tissue decreases, but thermal effects can still be significant even at greater distances.
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  • The study looked at patients who might have a disease called interstitial cystitis (IC) and checked to see if they had other confusing illnesses.
  • The researchers reviewed medical records of patients from 2005 to 2019, finding some had bladder or prostate cancer and a few had tuberculosis.
  • The results showed it's really important to keep checking for serious conditions like bladder tumors or tuberculosis in patients who might have IC, even after their initial tests.
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Purpose: To evaluate the efficacy and safety of holmium laser enucleation of the prostate (HoLEP) in a large prospective cohort of patients with benign prostatic hyperplasia (BPH) through systematic follow-up at a single institution.

Materials And Methods: Clinical outcomes were analyzed between August 2008 and June 2022. Patients were followed-up at 2 weeks, 3 months and 6 months postoperatively.

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Purpose: We aimed to evaluate the effect of self-training using a virtual reality head-mounted display simulator on the acquisition of surgical skills for holmium laser enucleation surgery.

Methods: Thirteen medical students without surgical skills for holmium laser enucleation of the prostate were trained using multimedia to learn the technique via simulator manipulation. Thereafter, participants performed the technique on a virtual benign prostatic hyperplasia model A (test A).

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Objective: To evaluate the effect of detrusor underactivity (DUA) on the postoperative outcomes of holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic hyperplasia (BPH).

Patients And Methods: Patients with BPH who underwent HoLEP between January 2018 and December 2022 were enrolled in this prospective database study. Patients were divided into DUA (bladder contractility index [BCI] <100) and non-DUA (BCI ≥100) groups.

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Introduction: This study aimed to assess overactive bladder (OAB) treatment patterns and factors associated with effectiveness and persistence.

Methods: A prospective, longitudinal, observational registry study of adults starting OAB therapy with mirabegron or antimuscarinics was undertaken. Primary endpoints were time from treatment initiation to discontinuation/switching; proportion who discontinued/switched; and reasons for discontinuation/switching.

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Accurate and continuous bladder volume monitoring is crucial for managing urinary dysfunctions. Wearable ultrasound (US) devices offer a solution by enabling noninvasive and real-time monitoring. Previous studies have limitations in power consumption and computation cost or quantitative volume estimation capability.

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Purpose: We aimed to identify the risk factors for salvage procedure (SP) required for refractory adenomatous tissue resistant to morcellation during holmium laser enucleation of the prostate (HoLEP).

Methods: Patients who underwent HoLEP between January 2010 and April 2020 at Seoul National University Hospital were analyzed. SPs were defined as cases of conversion to resection of the prostatic tissue using an electrosurgical loop after morcellation or secondary morcellation a few days after surgery or conversion to open cystotomy.

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Purpose: We evaluated the efficacy and safety of mid-term follow-up in low-power (LP) Holmium laser enucleation of the prostate (HoLEP) compared with high-power (HP) surgery for benign prostatic hyperplasia (BPH).

Materials And Methods: This prospective, single-blind, randomized controlled study was conducted between September 2020 and April 2021. Ninety male patients >50 years who underwent HoLEP for BPH were randomly assigned to HP (80 W/2 J/40 Hz) and LP (24 W/2 J/12 Hz) groups.

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Blocking the abrupt increase in systolic blood pressure associated with autonomic response during bladder hydrodistention in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) is essential for patient safety. We conducted this study to compare autonomic responses during bladder hydrodistention in patients with IC/BPS under general and spinal anaesthesia. Thirty-six patients were randomly allocated to a general anaesthesia (GA, n = 18) or a spinal anaesthesia (SA, n = 18) group.

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Article Synopsis
  • The study aimed to create a machine learning model to predict how patients with overactive bladder would respond to treatments with mirabegron or antimuscarinic agents, using data from the FAITH registry.
  • The researchers analyzed data from 396 patients, comparing outcomes based on their treatment's efficacy, persistence, and safety, and found that 34.8% had "more effective" treatment responses.
  • The decision tree model (C5.0) was determined to be the most effective algorithm, achieving a receiver operating characteristic area under the curve score of 0.70, indicating moderate predictive accuracy.
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Purpose: We assessed the effects of preoperative bladder compliance on the long-term functional outcomes, especially focused on postoperative storage symptom changes, after laser prostatectomy.

Materials And Methods: From January 2008 to March 2014, 1,608 men who underwent laser prostatectomy, including holmium laser enucleation or photo-vaporization of the prostate, were included in the analysis. We divided patients into 3 groups according to bladder compliance on a baseline urodynamic study: <12.

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Objectives: There is no consensus on the management plan for incidental prostate cancer (IPCa) after holmium laser enucleation of the prostate (HoLEP). This study aims to investigate the natural course of this disease and suggest appropriate treatment in real clinical practice.

Methods: The medical records of a prospective cohort of patients with LUTS/BPH who underwent HoLEP between July 2008 and December 2020 at Seoul National University Hospital were retrospectively reviewed.

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  • This study assesses how urinary retention affects the outcomes of holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic hyperplasia (BPH) and urinary symptoms.
  • A total of 903 patients were analyzed, with follow-up data showing significant improvements in urinary flow and postvoid residual volumes across groups, both with and without histories of urinary retention.
  • The findings indicate that patients with preoperative acute or chronic urinary retention experience similar enhancements in voiding symptoms and urinary flow after the procedure compared to those without urinary retention.
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Purpose: Bladder capacity is an important parameter in the diagnosis of lower urinary tract dysfunction. We aimed to determine whether the maximum bladder capacity (MCC) measured during a urodynamic study was affected by involuntary detrusor contraction (IDC) in patients with Lower Urinary Tract Symptoms (LUTS)/Benign Prostatic Hyperplasia (BPH).

Methods: Between March 2020 and April 2021, we obtained maximum voided volume (MVV) from a 3-day frequency-volume chart, MCC during filling cystometry, and maximum anesthetic bladder capacity (MABC) during holmium laser enucleation of the prostate under spinal or general anesthesia in 139 men with LUTS/BPH aged >50 years.

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Purpose: This study investigated functional outcomes in lower urinary tract symptoms (LUTS), the incidence of incidental prostate cancer (PCa), and changes in prostate-specific antigen (PSA) levels after holmium laser enucleation of the prostate (HoLEP) in patients with elevated PSA and benign prostatic hyperplasia (BPH).

Methods: A retrospective review of a prospectively designed protocol for patients who underwent HoLEP at our institution from January 2010 to May 2020 was conducted. Patients were classified into low-PSA (<3.

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Purpose: We aimed to identify risk factors for transurethral coagulation (TUC) using bipolar electrocautery for hemostasis during holmium laser enucleation of the prostate (HoLEP) surgery for benign prostatic hyperplasia (BPH).

Methods: We analyzed the clinical outcomes of HoLEP surgery performed by a single surgeon between January 2010 and April 2020 at the Seoul National University Hospital. Patient characteristics and perioperative parameters were used to identify the risk factors for TUC.

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Article Synopsis
  • The study aimed to investigate how common detrusor overactivity with impaired contractility (DOIC) is among older adults living in the community and whether it results from one or two separate bladder issues.
  • The research utilized a decade’s worth of urodynamic data and focused on evaluating different bladder functions, including storage and voiding capabilities, in elderly men and women.
  • Results indicated that DOIC occurs more frequently in men than women, with men showing worse voiding parameters, whereas, for women, DOIC appears to be a transitional stage from detrusor overactivity (DO) to detrusor underactivity (DU).
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Purpose: Advances in the diagnosis and treatment of prostate cancer have increased the patients' stress level and decreased the quality of life. A variety of instruments are currently available to evaluate patients with prostate cancer. However, only a few tools are available to assess Korean patients, and therefore we demonstrated a linguistic validation of Korean Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP).

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Lower urinary tract symptoms are highly prevalent and closely related to patients' quality of life. Clinical research on urologic disease is essential for accumulating evidence on patient management; however, the major obstacle is converting patients' subjective symptoms to objective parameters. The optimal application of well-developed and validated questionnaires is vital in achieving objectivity and minimizing bias in clinical research.

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Aims: This study aimed to investigate the efficacy and safety of mirabegron for Parkinsonism patients with overactive bladder (OAB) symptoms in a randomized, placebo-controlled, multicenter study.

Materials And Methods: Inclusion criteria are Parkinsonism with OAB symptoms for 4 weeks or more, OAB symptom score (OABSS) questionnaire scores greater than 2, and OABSS urgency question scores greater than 1. After a 2-week wash-out period, the patients were randomized into placebo and mirabegron groups at visit 2.

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Augmentation enterocystoplasty (AEC) is a surgical procedure in which the bladder is enlarged using an intestinal segment in patients with lower urinary tract dysfunction who fail to achieve satisfactory results with all conservative treatments. Currently, surgical materials and procedures, concomitant correction of upper urinary tract abnormalities, or bladder neck reconstruction may vary depending on the experience and preferences of the surgeons. AEC has been proven to be successful with respect to surgical goals, such as achieving urinary continence, improving quality of life, and preserving the upper urinary tract over the long term.

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Among transurethral surgery for benign prostatic hyperplasia (BPH), anatomical endoscopic enucleation of the prostate (AEEP) differs from conventional transurethral surgery as it adopts the same enucleation principle as open surgery. AEEP is known as an effective and safe surgical method. However, the learning curve is steep because the surgical anatomy is different from that of conventional transurethral surgery.

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