Quinine inhibits myogenic differentiation by disrupting AKT signaling pathway.

Sarcopenia is a disease characterized by decreased muscle fibers and mass. Although it mainly affects the older adults, it can also occur in various age groups as a secondary effect of medications used for treating certain diseases, such as cancer and diabetes. With population aging, sarcopenia has drawn significant attention owing to its increasing prevalence.

Enhanced cytomegalovirus infection in human trabecular meshwork cells and its implication in glaucoma pathogenesis.

Cytomegalovirus (CMV) is one of the infectious causes of hypertensive anterior uveitis, which is characterized by recurrent episodes of elevated intraocular pressure (IOP) and mild anterior uveitis. Despite the potentially vision-threatening complications of this disease, the underlying mechanisms remain largely undefined. We aimed to investigate whether human trabecular meshwork (TM) cells, the key cell type that regulates IOP, could support CMV replication, as well as demonstrate the relevant pathological changes in TM.

Synthesis and Characterization of ZIF-7 Membranes by In Situ Method.

Zeolitic imidazolate frameworks (ZIFs) have been the focus of interest in adsorption, catalysis, and membrane applications due to their superior thermal and chemical stability, tunable microporous channels, and tailorable physical/chemical properties. In this study, ZIF-7 membranes were successfully prepared on macroporous a-alumina substrate by in situ solvothermal method, without the necessity of seeding or surface modification step. Addition of sodium formate during the reaction facilitates continuous well-intergrown crystalline ZIF-7 layer.