Publications by authors named "Seung Ii Kim"
Background: Extracellular vesicles (EVs) regulate cell metabolism and various biological processes by delivering specific proteins and nucleic acids to surrounding cells. We aimed to investigate the effects of the cargo contained in EVs derived from adipose-derived stem cells (ASCs) on the porcine embryonic development.
Methods: ASCs were isolated from porcine adipose tissue and characterized using ASC-specific markers via flow cytometry.
Article Synopsis
- Oocytes have the potential to reprogram somatic cells into totipotent cells, and this study focuses on isolating and characterizing newly identified intra-ooplasmic vesicles (IOVs) from mature porcine oocytes.
- The IOVs were found to average 186.3 nm in size and contained proteins related to important biological functions such as reprogramming, stress response, and metabolism.
- When fibroblasts were treated with IOVs, there were significant changes, including increased expression of pluripotency markers and alterations in cell shape, indicating potential for developing stem cells through reprogramming.
Purpose: This study aimed to examine the prevalence and trends of breast cancer-related risk factors and characteristics in premenopausal underweight Korean women according to birth year cohort.
Methods: Socioeconomic and breast cancer-related risk factors were investigated in 13,415 premenopausal women using nationwide cross-sectional surveys performed between 2007 and 2015. Underweight was defined as body mass index < 18.
We aimed to identify metabolites involved in the anti-obesity effects of (PG) in high-fat diet (HFD)-fed mice using mass spectrometry (MS)-based metabolomic techniques. C57BL/6J mice were divided into four groups: normal diet (ND)-fed mice, HFD-fed mice, HFD with 1% PG extract-fed mice (HPGL), and HFD with 5% PG extract-fed mice (HPGH). After 8 weeks, the HFD group gained more weight than the ND group, while dietary 5% PG extract attenuated this change.
View Article and Find Full Text PDFThe secretion of extracellular membrane vesicles (EMVs) is a common phenomenon that occurs in archaea, bacteria, and mammalian cells. EMVs contain biologically active proteins, which have diverse roles in biological processes. The outer membrane vesicles (OMVs) of Gram-negative bacteria and membrane vesicles (MVs) of Gram-positive bacteria have been discovered in various species.
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