Publications by authors named "Seung Gu Yang"
Investigation of Anti-Liver Cancer Activity of the Herbal Drug FDY003 Using Network Pharmacology.
Evid Based Complement Alternat Med
September 2022
Article Synopsis
- Liver cancer is a major global health issue, ranking as the sixth-most common and second-most deadly cancer, causing around 830,000 deaths yearly.
- This study explores the effects of a herbal drug called FDY003, which was found to reduce the growth of liver cancer cells and increase their sensitivity to chemotherapy.
- The research identified 16 active compounds in FDY003 that interact with 91 targets involved in liver cancer progression, affecting key biological processes and important signaling pathways related to the disease.
Pancreatic cancer (PC) is the most lethal cancer with the lowest survival rate globally. Although the prescription of herbal drugs against PC is gaining increasing attention, their polypharmacological therapeutic mechanisms are yet to be fully understood. Based on network pharmacology, we explored the anti-PC properties and system-level mechanisms of the herbal drug FDY003.
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