Publications by authors named "Seulji Kim"

Inflammatory bowel disease is associated with a high risk of colitis-associated cancer (CAC). We evaluated the role of TLR3 in CAC using a murine model. Wild-type (WT) and TLR3-knockout (TLR3) mice received azoxymethane (AOM) 12.

View Article and Find Full Text PDF
Article Synopsis
  • Inflammatory bowel disease (IBD), once seen primarily in Western countries, is now on the rise in Asia, with notable differences in how it affects populations there compared to the West.
  • This study focused on South Korea, analyzing data from 2010 to 2018 to assess new cases, incidence rates, medication trends, and clinical outcomes of Crohn's disease (CD) and ulcerative colitis (UC).
  • Results showed that CD incidence has stabilized, while UC rates are increasing, particularly among younger patients, and there has been a shift towards using more modern treatments like immunomodulators and biologics, resulting in improved clinical outcomes over time.*
View Article and Find Full Text PDF

It has been reported that migraine is more common in patients with inflammatory bowel disease (IBD) than in general. However, the impact of migraine on the development of IBD has not yet been elucidated. The aim of this study was to determine the association between migraine and the development of IBD.

View Article and Find Full Text PDF

Background: Prevalence of depression and anxiety are known to be increased in patients with inflammatory bowel disease (IBD), but it is unclear whether such elevations adversely affect IBD outcomes.

Objective: We aimed to investigate the association between depression or anxiety and clinical outcomes of IBD.

Method: Using claims data from the South Korean National Health Insurance Service (NHIS), patients with IBD were identified by codes of the International Classification of Disease, 10th Revision (ICD-10) and the Rare/Intractable Disease (RID) registration program for years 2010 to 2017.

View Article and Find Full Text PDF