Publications by authors named "Settha Sinthasak"
Article Synopsis
- The study evaluates the pandemic potential of H5N1 viruses from poultry outbreaks in Lao PDR between 2006 and 2008, analyzing 29 virus samples and two from human cases.
- It identifies mutations in the viruses that may confer resistance to antiviral drugs, such as oseltamivir and amantadine, raising concerns for potential pandemic threats.
- Additionally, the researchers discovered new H5N1 reassortants with different genetic characteristics, emphasizing the need for enhanced surveillance measures to monitor these evolving viruses.
Despite the extensive use of poultry vaccines to control the spread of H5N1 influenza in poultry, H5N1 outbreaks continue to occur in domestic birds. Our objective was to determine the duration of the neutralizing antibody response under field conditions after vaccination with a laboratory-tested inactivated reverse genetics-derived H5N3 vaccine. H5N3 hemagglutination inhibition (HI) and virus neutralization (VN) antibodies were observed 40 weeks after vaccination of chickens with two doses and vaccination of ducks with one dose.
View Article and Find Full Text PDFA prospective surveillance program for influenza viruses was established in Lao People's Democratic Republic (PDR) in July of 2005. We report isolation of H5N1 virus genetically distinct from H5N1 circulating in 2004, which indicates reintroduction of H5N1 into Lao PDR after its disappearance (i.e.
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