Nesolagus netscheri, a Sumatran striped rabbit, is one of the rarest rabbits in the Leporidae family, and its genetic information is still limited. This study provides the first mitochondrial genome and molecular systematic characterization of the Sumatran striped rabbit, Nesolagus netscheri, Indonesia's rarest rabbit. It consists of a circular double-stranded DNA of 16,709 bp.
View Article and Find Full Text PDFObjectives: In the context of military health, removable partial acrylic dentures (RPADs) are crucial for the quality of life and performance of Indonesian National Armed Forces (TNI) soldiers. Given the demanding and unpredictable military environment, RPADs provide a solution for soldiers experiencing tooth loss. This research aims to identify behavioral factors influencing the lifespan of RPADs among TNI soldiers.
View Article and Find Full Text PDFCurr Issues Mol Biol
November 2024
The limited availability of corneal tissue grafts poses significant challenges in the treatment of corneal blindness. Novel treatment utilizes stem cell grafts transplanted from the healthy side of the cornea to the damaged side. However, this procedure is only possible for those who have one-sided corneal blindness.
View Article and Find Full Text PDFAn extended microkinetic model (MKM) for the selective oxidation of ethylene to ethylene oxide (EO) is presented, based on an oxidic representation of the silver (Ag) surface, namely, the p(4 × 4) oxidic reconstruction of the Ag(111) phase to mimic the significant oxygen coverage under reaction conditions, as is evidenced by recent operando spectroscopic studies. The MKM features three pathways each for producing either ethylene oxide (EO) or carbon dioxide (CO), including the common intermediate or oxometallacycle (OMC) pathway, an atomic oxygen pathway, as well as pathways centered around the role of a diatomic oxygen species occupying an oxygen vacancy (O/O*). The MKM uses a composite set of experimental and density functional theory (DFT) kinetic parameters, which is further optimized and trained on experimental reaction data.
View Article and Find Full Text PDFThe success of international startups is profoundly influenced by their adeptness in utilizing dynamic marketing capabilities (DMCs) and strategic information management (SIM) to achieve competitive advantage and sustainable growth in global markets. This research examines the effects of these crucial elements on the success of international startups through a meta-narrative analysis. By synthesizing findings from 20 articles published in Scopus-indexed journals between 2020 and 2024, we aim to provide an in-depth understanding of the interaction between DMCs and SIM and their impact on startup performance in global markets.
View Article and Find Full Text PDFThis study explores the potential of Indonesian herbal compounds against the chikungunya virus (CHIKV), which causes widespread illness without a specific cure known as chikungunya fever (CHIKF). By focusing on the nsP2 protein, crucial for the virus's replication, the research utilizes computational methods identifying inhibitor compounds with high binding affinity. These promising candidates are further analyzed through 1 µs of molecular dynamic (MD) simulation studies, aiming to find effective inhibitors to control the chikungunya spread, leveraging Indonesia's rich biodiversity for novel anti-CHIKV therapies.
View Article and Find Full Text PDFBackground: The growing recognition of advanced practice nurses' role has been challenged by the need for decreased health-care costs while ensuring quality of care and patient well-being. However, limited evidence exists from previous reviews evaluating the effectiveness of advanced practice nurses.
Objectives: To investigate the effects of advanced practice nurses on health-care costs, quality of care, and patient well-being.
Introduction As a medical condition, obesity is a global public health concern that still has no satisfactory solution. Endoscopic sleeve gastroplasty (ESG) and intragastric balloon (IGB) are proven to be safe and efficient in producing weight loss. Endoscopic sleeve gastroplasty has achieved significant success; therefore, it is timely to compare it to intragastric balloon therapy.
View Article and Find Full Text PDFThe prevalence of human immunodeficiency virus (HIV) among adolescents is on the rise due to a lack of comprehensive knowledge, leading to suboptimal attitudes and behaviors, which emphasizes the critical need for targeted interventions. The aim of this review study was to evaluate the effectiveness of educational interventions for HIV prevention among adolescents by assessing their impact on knowledge, attitude, and behavior. A systematic review of seven databases: PubMed, Science Direct, Cochrane, JSTOR, Embase, Scopus, and EBSCO were identified, and 14 eligible randomized controlled trials published until June 2023 were included.
View Article and Find Full Text PDFBackground: Globally, loneliness is a growing public health concern associated with poor mental and physical health among older adults. Therefore, we performed a meta-analysis to explore the prevalence of loneliness and associated risk factors among older adults across six continents.
Methods: Web of Science, PubMed, Embase, CINAHL, Cochrane Library, and references lists were comprehensively searched until April 2024.
Introduction: Gastric perforation is a rare occurrence, particularly in neonates. This is an emergency case in this population. The incidence of spontaneous gastric perforation in neonates is 1:2900 live births, with high mortality and morbidity rates.
View Article and Find Full Text PDFThis study presents a structural phylogenetic analysis of plant defensive peptides, revealing their evolutionary relationships, structural diversification, and functional adaptations. Utilizing a robust dataset comprising both experimental and predicted structures sourced from the RCSB Protein Data Bank and AlphaFold DB, we constructed a detailed phylogenetic tree to elucidate the distinct evolutionary paths of plant defensive peptide families. Our findings showcase the evolutionary intricacies of defensive peptides, highlighting their diversity and the conservation of key structural motifs critical to their antimicrobial or defensive functions.
View Article and Find Full Text PDFBackground: Infants are in a critical period during which often occur many problems, such as growth, development, and motor delays. One of the interventions that can potentially reduce these problems is by giving a massage therapy.
Purpose: This study aims to conduct a systematic scoping review of massage therapy's potential for growth and development among infants under nine months.
Photoacoustic imaging is a hybrid modality that combines high-contrast and spectroscopy-based optical imaging specificity with the high spatial resolution of ultrasonography. This review highlights the development and progress of photoacoustic imaging technology over the past decade. This imaging technology has evolved to be more user-friendly, cost-effective, and portable, demonstrating its potential for diverse clinical applications.
View Article and Find Full Text PDFBackground: Indonesia has rapidly embraced digital health, particularly during the COVID-19 pandemic, with over 15 million daily health application users. To advance its digital health vision, the government is prioritizing the development of health data and application systems into an integrated health care technology ecosystem. This initiative involves all levels of health care, from primary to tertiary, across all provinces.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic prompted adjustments in education, raising concerns about students' competency achievement. Despite these changes, aspects like student engagement (SE), basic needs fulfillment (BNF), and stress levels (SL) in nursing students during community-based clinical practice remain understudied.
Objectives: This study aims to examine the relationships between students' competencies achievement (SCA), student engagement, basic needs fulfillment, and stress levels among nursing students engaging in community-based clinical practice during the COVID-19 pandemic.
Background: Managing dental care in children with special health care needs poses distinct challenges. This case report explores these challenges within the context of a 9-year-old boy with Down syndrome (DS) facing dental treatment refusal. Over ten months and 13 visits, a tailored approach was devised for the patient who presented with multiple cavities and retained primary teeth.
View Article and Find Full Text PDFObjective: This study aimed to investigate the levels of chitinase-3-like protein-1 (CHI3L1), matrix metalloproteinase-9 (MMP-9), and monocyte chemoattractant protein-1 (MCP-1) in adenomyosis, as compared to normal myometrial tissue. These biomarkers may be useful for determining potential treatment targets.
Methods: This was a correlative, analytical, and observational study with a cross-sectional design.
Linear assumption on the level of stiffness in a tissue shows a significant correlation with disease. Photoacoustic imaging techniques that are non-contact by design have been developed in this study to detect differences in phantom (soft tissue mimicking materials) stiffness. This study aims to detect differences in phantom stiffness based on the results of image reconstruction at the resonance frequency.
View Article and Find Full Text PDFSeveral catastrophic building collapses occur because of the propagation of local-initial failures. Current design methods attempt to completely prevent collapse after initial failures by improving connectivity between building components. These measures ensure that the loads supported by the failed components are redistributed to the rest of the structural system.
View Article and Find Full Text PDFMicroorganisms quickly colonise microplastics entering the ocean, forming a biofilm that, if ingested, is consumed with the microplastics. Past research often neglects to expose fish to biofouled microplastics, opting only for clean microplastics despite the low likelihood that fish will encounter clean microplastics. Here, we investigate the physiological impacts of biofouled polyethylene microplastic (300-335 μm) exposure in juvenile fish.
View Article and Find Full Text PDFThe fungal genus is a rich source of structurally diverse secondary metabolites with remarkable pharmaceutical properties. The chemical constituents and anticancer activities of the marine-derived fungus have never been investigated. In this study, a bioactivity-guided investigation led to the isolation of eleven compounds, including trichodermamide A (), trichodermamide B (), aspergillazine A (), DC1149B (), ergosterol peroxide (), cerebrosides D/C (), 5-hydroxy-2,3-dimethyl-7-methoxychromone (), nafuredin A (), and harzianumols E/F (/).
View Article and Find Full Text PDF