Publications by authors named "Seth Osei Asiedu"
Article Synopsis
- Mycolactone (MLN) is a toxin that significantly inhibits platelet degranulation and exocytosis, and it also has strong effects on endocytosis by binding to clathrin and a novel SARS-CoV-2 fusion protein.
- In live viral assays, MLN showed 100% inhibition at 60 nM and was found to be 10 times more effective than the antiviral drugs remdesivir and molnupiravir.
- The compound demonstrated notable cytotoxicity against various human cell lines, but it maintained a high therapeutic index, making it a promising candidate for treating COVID-19 and other similar viruses.
