Publications by authors named "Seth Klapman"
Article Synopsis
- The study investigated how glucagon-like peptide 1 (GLP-1) receptor agonist therapy affects the presence of residual gastric contents in patients who fasted before undergoing esophagogastroduodenoscopy (EGD).
- Researchers compared two groups: 90 patients taking GLP-1 agonists during the procedure and 102 patients who had started the therapy within 1,000 days after EGD, excluding cases of urgent procedures or prior gastric issues.
- Results showed that the GLP-1 group had a significantly higher rate of visible gastric contents (19%) compared to the control group (5%), indicating a potential increased risk of pulmonary aspiration during procedures.
This cross-sectional study examines undetectable heart sounds in hospitalized patients who are undergoing echocardiography and evaluates the association between patient factors and missed valvular heart disease diagnoses.
View Article and Find Full Text PDFSignificance: After a dilated eye examination, many patients experience symptoms of prolonged light sensitivity, blurred vision, and cycloplegia associated with pharmacological mydriasis. Phentolamine mesylate ophthalmic solution (PMOS) may expedite the reversal of mydriasis in patients, potentially facilitating return to functional vision and reducing barriers to obtaining dilated eye examinations.
Purpose: The protracted reversal time after pharmacologically induced pupil dilation impairs vision.
Purpose: Phentolamine mesylate ophthalmic solution (PMOS), applied to the eye topically, was shown previously to have beneficial effects in patients with dim light vision disturbances (DLD), including decreased pupil diameter (PD), improved best-corrected distance visual acuity (BCDVA), as well as lower intraocular pressure (IOP). The ORION-1 trial evaluated the long-term safety and efficacy of PMOS in a glaucomatous, presbyopic population.
Patients And Methods: In this randomized, double-masked, multi-center, placebo-controlled, multiple-dose Phase 2b trial, 39 patients with elevated IOP were randomized to receive one evening dose of study medication or placebo for 14 days.
Objective: Ensuring the ability to exchange patient information among disparate electronic health records systems is a top priority and a domain of substantial public investment across countries. However, we know little about the extent to which current capabilities meet the needs of frontline clinicians.
Materials And Methods: We conducted in-person, semistructured interviews with emergency care physicians and nurses in select hospitals in Canada, Denmark, Finland, Germany, and the USA.