Revisiting Skeletal Dysplasias in the Newborn.

With over 400 reported disorders, the skeletal dysplasias represent a myriad of molecularly-based skeletal abnormalities. Arising from errors in skeletal development, the clinical spectrum of disease evolves through an affected individual's life. The naming and grouping of these disorders are ever-changing, but the fundamentals of diagnosis remain the same and are accomplished through a combination of prenatal ultrasonography and postnatal physical examination, radiography, and genetic analysis.

Lack of utility of tracheal aspirates in the management of suspected pneumonia in intubated neonates.

Objectives: To evaluate the utility of tracheal aspirates in suspected pneumonia in intubated neonates and to measure the burden of antibiotic use associated with a positive tracheal aspirate culture.

Design: Retrospective cohort study between January 2016 and December 2017.

Setting: A level IV neonatal intensive care unit (NICU).