Publications by authors named "Seth Ginsberg"

Article Synopsis
  • This study examined how women's beliefs about the safety of arthritis medications and their interactions with healthcare providers affect their choices regarding medication use during pregnancy and breastfeeding.
  • Conducted through a survey with inflammatory arthritis patients, findings indicated that many women discontinued effective treatments due to safety concerns and inconsistent advice from providers, with 15% of pregnancies involving methotrexate exposure.
  • The results highlight the need for improved communication and family planning support for women with arthritis who are pregnant or lactating, as many opt to manage their condition without medication to avoid potential risks to their babies.
View Article and Find Full Text PDF

Objective: Women with inflammatory arthritis appear to have fewer children as compared with healthy women, but few studies have assessed how patients' attitudes and decision making influence their family sizes. Little is also known about how patients experience other aspects of their reproductive lives, such as menstruation and contraception.

Methods: We partnered with ArthritisPower, a patient-powered research network, and its associated online patient community, CreakyJoints, to create and disseminate a survey among female members aged 18-50 years with inflammatory arthritis.

View Article and Find Full Text PDF

This article aims to describe key issues, processes, and outcomes related to development of a patient registry for rheumatology research using a digital platform where patients track useful data about their condition for their own use while contributing to research. Digital interventions are effective to build a patient research registry for people with rheumatoid arthritis and other rheumatic and musculoskeletal diseases. ArthritisPower provides evidence of the value of digital interventions to build community support for research and to transform patient engagement and patient-generated data capture.

View Article and Find Full Text PDF

Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are common in women of childbearing age and are often treated with teratogenic medications. In this study, we assessed contraceptive methods in young women with RA or PsA and correlated contraceptive method efficacy with use of concomitant rheumatic medications. We combined the data from several cross-sectional surveys of women under the age of 40 with RA or PsA.

View Article and Find Full Text PDF

Purpose: Despite American College of Rheumatology recommendations, appropriate and timely initiation of biologic therapies does not always occur. This study examined openness to and preference for attributes of biologic therapies among patients with rheumatoid arthritis (RA), differences in patients' and rheumatologists' perceptions, and discussions around biologic therapy initiation.

Patients And Methods: A self-administered online survey was completed by 243 adult patients with RA in the US who were taking disease-modifying antirheumatic drugs (DMARDs) and had never taken, but had discussed biologic therapy with a rheumatologist.

View Article and Find Full Text PDF

Objective: To develop a new evidence-based, pharmacologic treatment guideline for rheumatoid arthritis (RA).

Methods: We conducted systematic reviews to synthesize the evidence for the benefits and harms of various treatment options. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to rate the quality of evidence.

View Article and Find Full Text PDF

Objective: To develop a new evidence-based, pharmacologic treatment guideline for rheumatoid arthritis (RA).

Methods: We conducted systematic reviews to synthesize the evidence for the benefits and harms of various treatment options. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to rate the quality of evidence.

View Article and Find Full Text PDF

Objective: To examine the patterns of methotrexate (MTX) use among rheumatoid arthritis (RA) patients.

Methods: Using data from RA patients enrolled in a US commercial health plan and the US Medicare program, we identified RA patients initiating oral MTX. Persistence with MTX (oral or subcutaneous [SC]) was defined as no gap for ≥90 days.

View Article and Find Full Text PDF