Deoxy-ribonucleic acid repair genes XRCC1 and XPD polymorphisms and brain tumor risk.

Objectives: To evaluate whether polymorphisms in the deoxy-ribonucleic acid (DNA) repair genes XRCC1 and XPD, have efficacy in the development of brain tumors.

Methods: This is a case-population based study, including 135 cases of brain tumors, and 87 population based age- and gender-matched healthy controls. We examined the role of XRCC1 Arg 399Gln gene and XPD Lys751Gln gene polymorphisms, in the context of brain tumor risk for the Turkish population between 2004 and 2007 at Selcuk University, Konya, Turkey.