Candidate Genetic Markers for Post Traumatic Stress Disorder Within the Scope of Forensic Psychiatry.

Objective: This study was conducted to investigate the role of two candidate polymorphisms to improve the diagnosis of Post-Traumatic StressDisorder (PTSD) in forensic psychiatry settings.

Methods: Individuals who applied to our unit with PTSD symptoms following a traffic accident were included. The control group consisted of people who had experienced a similar accident without any symptoms.

Web Survey of Turkish Pharmacy Students Comparing First and Fifth Years' Antidepressant Awareness and Stigmatizing Attitudes Regarding Depression and Anxiety.

The prevalence of depression and anxiety has increased day by day. Prejudice, self-stigma, and public stigma, on the other hand, continue to prevent patients from seeking adequate treatment, particularly in traditional communities. In this web-based, cross-sectional study, both the presence of depression and anxiety, and the knowledge, attitude, and awareness of first- and fifth (final)-year pharmacy students were examined via an online survey.

Safety of lorlatinib in ALK-positive non-small-cell lung cancer and management of central nervous system adverse events.

The use of tyrosine kinase inhibitors has made a breakthrough in the treatment of non-small-cell lung cancer (NSCLC). Recently, lorlatinib, a third-generation tyrosine kinase inhibitor, has demonstrated significant systemic and intracranial activity in both first-line and subsequent-line therapy in ALK-positive NSCLC patients. In this review, general characteristics of lorlatinib, its efficacy in the treatment of ALK-positive NSCLC patients and the safety of lorlatinib, particularly addressing central nervous system adverse events, are discussed.

Valproate, obesity and other causes of clozapine poor metabolism in the context of rapid titration may explain clozapine-induced myocarditis: A re-analysis of a Turkish case series.

Introduction: Clozapine-induced myocarditis or any clozapine-induced inflammation may be a hypersensitivity reaction due to titration that was too rapid for the patient's clozapine metabolism. Clozapine metabolism is influenced by ancestry, sex, smoking and the presence of confounders including obesity, infections, and inhibitors (e.g.

Do Changes in Body Shape Due to Pregnancy Lead to Cosmetic Surgery? A Cross-Sectional Study.

Objective: Pregnants and puerperas show different perceptions of their body image and appearance, so authors investigated their perceptions related to pregnancy and puerperium, evaluating their views on cosmetic surgery, by a cross-sectional study.

Materials And Methods: 5-item questionnaires were administrated to women at first pregnancy and puerperas. Patients were submitted also to Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI) and Body Image Inventory (BII) analysis, indicating the level of anxiety, depression and body dissatisfaction for somatic changes during pregnancy and after childbirth.

The Validity and Reliability of the Turkish Version of MacArthur Competence Assessment Tool for Treatment Decision: Correlates of Competence in Schizophrenia Patients.

Introduction: Informed consent is an indispensable condition of the clinical practice for the provision of health care. The main objective of this study is to translate the MacArthur competence assessment tool for treatment (MacCAT-T) into Turkish and evaluate the validity and reliability of the Turkish version in schizophrenia patients and healthy control subjects.

Methods: In this cross-sectional study, 30 hospitalized schizophrenia patients and 25 healthy subjects were assessed with MacCAT-T, Mental Competence Evaluation Form for Assessment of Competency (MCEF), Positive and Negative Syndrome Scale, Beck Depression Inventory, Mini Mental State Examination, Wechsler Adult Intelligence Scale (WAIS) - Similarities subtest and the Schedule for Assessing the Three Components of Insight.

A Forensic Psychiatric Perspective on the Draft Mental Health Act of Turkey in Light of Similar Laws and Practice in a Foreign Jurisdiction.

Objective: Designated Acts for issues related to mental health are in force in many countries throughout the world. A mental health act is also expected to be approved in Turkey soon. Under the leadership of the Psychiatric Association of Turkey, non-governmental organizations operating in the field of mental health has contributed to the emergence of a comprehensive draft.

Perspectives, fears and expectations of patients with gynaecological cancers during the COVID-19 pandemic: A Pan-European study of the European Network of Gynaecological Cancer Advocacy Groups (ENGAGe).

Background: The impact of the COVID-19 pandemic on European gynaecological cancer patients under active treatment or follow-up has not been documented. We sought to capture the patient perceptions of the COVID-19 implications and the worldwide imposed treatment modifications.

Methods: A patient survey was conducted in 16 European countries, using a new COVID-19-related questionnaire, developed by ENGAGe and the Hospital Anxiety & Depression Scale questionnaire (HADS).

The Effect of Life Skills Training on Functioning in Schizophrenia: A Randomized Controlled Trial.

Objective: Psychosocial approaches including occupational therapeutic interventions constitute an important part of mental health treatments. This research was planned to investigate the effects of individualized life skills training on the functionality of individuals diagnosed with schizophrenia.

Method: A total of 32 individuals diagnosed with schizophrenia were assigned randomly to the study (n=15) and the control groups (n=17).

A comparative study of detection of myocarditis induced by clozapine: With and without cardiac monitoring.

The aim of this study was to investigate and compare the incidence of suspected or definite cases of clozapine induced myocarditis (SDM) and clinical factors which could influence its onset in two different time periods, defined by pre- and post-cardiac monitoring at an inpatient setting, during the initiation phase of clozapine treatment. Hospital records of patients started on clozapine in the inpatient unit between 2011 and 2018 were investigated. Eight in 38 patients (11.

Compliance in schizophrenia spectrum disorders: the role of clinical pharmacist.

The inability of patients with psychiatric illness to achieve full compliance with treatment during the postdischarge period is a major problem. In this study, our aim was to evaluate whether drug education provided by a clinical pharmacist during discharging period has an effect on compliance. Forty adult patients diagnosed with psychotic disorders were included.

Does Gender Affect the Relationship Between Anxiety Sensitivity and Social Anxiety?

Objective: Although there are studies on the effects of gender and time on social anxiety and anxiety sensitivity, there is no consensus on how these variables moderate the relationship between the two. The aim of this study was to examine the effect of the last year of medical school on social anxiety and to determine the predictors of social anxiety, focusing mainly on gender and anxiety sensitivity.

Methods: The study was conducted at two time points.

Columellar Scar Perception in Open Rhinoplasty. Interplay of Scar Awareness, Body Cathexis and Patient Satisfaction.

Introduction: Open and closed approaches for rhinoplasty have individual advantages and disadvantages; however, the resultant columellar scar of the open approach is directly considered as a disadvantage. This study focuses on the columellar scar awareness and its implications on overall satisfaction of the patients after open rhinoplasty.

Patients And Methods: A total of 91 patients who have undergone open rhinoplasty were included in this study.

[The validity and reliability study of MBPI (Multidimensional Blood/Injury Phobia Inventory)].

Objective: This study aims to translate the 40-item MBPI (Multidimensional Blood/Injury Phobia Inventory) into Turkish and examination the reliability and validity figures of this scale.

Method: Trained interviewers assessed 477 factory workers using a battery of self-report measures including demographic information and MBPI that had been translated into Turkish by the study team. 61 of the 477 were also interviewed face-to-face by the investigator using the anxiety disorders/phobias sections of the CIDI (Composite International Diagnostic Interview).

Anxiety sensitivity: another reason to separate dental fears from blood-injury fears?

Although dental phobia is classified under the heading of blood-injury phobia, studies show differences between the two conditions in terms of frequency of fainting and gender distribution. Anxiety sensitivity (AS), which refers to discomfort and negative attributions to bodily anxiety sensations, was useful in differentiating panic anxiety from other phobic anxieties. No study has compared dental phobia with blood-injury phobia directly.

Escitalopram-induced Parkinsonism.

Objective: Since the early reports associating extrapyramidal side effects (EPS) to serotonin reuptake inhibitors (SSRI), SSRIs have been pointed as more common offenders among antidepressants in producing EPS. The induction of EPS by SSRIs has been thought to be a consequence of serotonergically mediated inhibition of the dopaminergic system. We would like to present a case of escitalopram-induced Parkinsonism to increase awareness of this clinical problem.