Publications by authors named "Serpil Albayrak"
Allergic reactions to enzyme replacement therapy in children with lysosomal storage diseases and their management.
J Pediatr Endocrinol Metab
October 2024
Article Synopsis
- Enzyme replacement therapy (ERT) can effectively manage lysosomal storage diseases, but it may cause hypersensitivity reactions in some patients.
- A study reviewed medical records of pediatric patients to assess the frequency and characteristics of these allergic reactions, finding that 25.3% experienced them, with anaphylaxis occurring in 6 cases.
- Management of hypersensitivity may include premedication and slower infusions, and some patients may require desensitization protocols to continue ERT safely.