Publications by authors named "Serkan Akan"

Penile prosthesis implantation is considered a last-resort treatment for erectile dysfunction, used when pharmacological and other conservative treatments are inadequate or at the patient's request. The well-documented complications of penile prostheses include pain, infection, mechanical failure, improper positioning, and erosion. In this case, we report a patient presenting with penile skin necrosis, despite the absence of typical risk factors such as diabetes mellitus, atherosclerosis, or chronic renal failure, attributed to pressure from a condom catheter that was used 15 years after the inflatable penile prosthesis implantation.

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Objective: To investigate whether the timing of bacillus Calmette-Guerin instillation (TTBCG), which plays a key role in treating non-muscle invasive bladder cancer (NMIBC), after transurethral resection of bladder tumor (TURBT) affects oncologic outcomes.

Methods: Patient data obtained from the Urologic Cancer Database- Bladder (UroCaD-B) of Turkish Uro-oncology Association (TUOA) were evaluated. Data from 292 patients from 12 centers with primary T1HG treated with TURBT and maintenance BCG between 2003 and 2023 were retrospectively analyzed.

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The holmium laser enucleation of the prostate (HoLEP) is a widely accepted and reliable treatment for benign prostatic hyperplasias. In developing countries where HoLEP surgery has only recently been introduced, its popularity is steadily increasing. In our case, the patient's history of HoLEP and the image of the irregular mass extending from the anterior bladder wall into the lumen were initially misdiagnosed as bladder cancer.

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Introduction: To evaluate the validity and reliability of the Turkish version of the Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index-10 (LURN SI-10).

Materials And Methods: In this, single-centre study, patients between 18 and 65 years old, who were suffering from lower urinary tract symptoms (LUTS) without any known urinary tract disease and on no medication, were enrolled. The control group consisted of participants, who were admitted to our clinic suffering from any complaint except LUTS and met all of the other inclusion and exclusion criteria.

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Article Synopsis
  • - Acrochordons are small, skin-colored growths commonly found in skin folds but are very rare on the penis.
  • - This report highlights a unique case of a penile acrochordon that is positive for androgen receptors and experienced rapid growth during puberty.
  • - The lesion's growth occurred without any known underlying health issues, like acromegaly or obesity, suggesting it may be an unusual case in medical literature.
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Background: Use of ureteral stents has become an integral part of urological practice. However, it also brought with it many complications. Double J (DJ) stent knotting is a rare stent complication, and only a few cases have been reported in the literature.

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Introduction - Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy. In the vast majority of patients, 1-4 weeks before the onset of GBS-related symptoms, an event such as upper respiratory tract or gastrointestinal tract infection, surgical intervention or vaccination is present. To the best of our knowledge, this is the first case of GBS that occurred after intravesical Bacillus Calmette-Guérin (BCG) therapy in the absence of tuberculosis or any other infection in the English literature.

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Purpose: to investigate the factors affecting post-treatment paternity intention in patients followed up after the diagnosis of testicular cancer and to make recommendations for the early postoperative period based on the identified factors.

Materials And Methods: This prospective descriptive study included total 185 patients who presented to our outpatient clinic between February 2000 and July 2020 who had radical orchiectomy due to suspected testicular cancer based on physical examination and other assessments. Contact information was found for 88 of 185 patients, and accordingly, the patients were reached by one-to-one phone calls.

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We, herein, present a case of a micropapillary variant of bladder cancer metastasizing to lymph nodes in an 87-year male with elevated serum carcinoembryonic antigen (CEA) levels (2637.8 ng/mL). The patient was evaluated for dyspeptic symptoms and elevated CEA levels.

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Objective: We aimed to determine which method gives the most consistent results between urethral monopolar cauterization and standard urethral partial ligation methods for the urethral obstruction model.

Methods: Thirty male rats were randomly divided into control, partial ligation, and monopolar cauterization groups. Six weeks after experimental procedures, the experimental groups were evaluated cystometrically, biochemically, and histologically.

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Background: Patients with high-risk prostate cancer (PCa) experience heterogeneous oncological outcomes. In this study, we assessed the patients who underwent an RP procedure because of high-risk prostate cancer in subgroups formed according to D'Amico criteria and analyzed the effects of these criteria on biochemical recurrence (BCR) after RP.

Methods: We retrospectively identified high-risk non-metastatic PCa patients who underwent RP between 2006 and 2020 in our hospital.

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Semen analysis and physical examination are performed while first evaluation for patients with male infertility. Alcohol, smoking and dietary habits can affect the semen parameters. This study aimed to evaluate whether semen parameters are changed with sexual arousal.

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We present a case of a 49-year Turkish woman who had synchronous renal leiomyoma and breast cancer. The patient was evaluated for a suspicious breast mass; and renal mass was detected incidentally by contrast-enhanced computed tomography (CT). Diagnostic tru-cut biopsy was performed for both masses.

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Background: Fibroepithelial polyps located in the ureter constitute 2-6% of all benign tumors in the urinary system. Distinguishing these lesions from transitional cell carcinoma is essential to avoid unnecessary nephroureterectomy.

Case Presentation: A 59-year-old asymptomatic caucasian male patient was enrolled in follow-up for Ta low-grade transitional cell bladder cancer 4 years ago in our clinic.

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Objective: This study aims to analyze the challenges, approaches and long-term results of primary or metachronous prostate cancer (PCa) in cases with multiple primary genitourinary cancers.

Methodology: A total of 17 patients were included in the study. Patients with multiple primary genitourinary cancers were divided into two groups according to the diagnosis of primary or metachronous PCa as group 1 and group 2.

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Background: This study aimed to determine the contribution of color Doppler ultrasonography (CDUS) performed before varicocelectomy to the success of surgical treatment and to evaluate the correlation between CDUS findings and semen parameters.

Methods: A total of 84 patients diagnosed with grade 3 left varicocele in our clinic between 2016 and 2018 were evaluated. The patients in whom the decision for varicocelectomy was based on only physical examination (PE) findings and abnormal semen analysis (SA) were defined as Group 1, while the patients undergoing varicocelectomy based on PE, CDUS and SA findings were defined as Group 2.

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Introduction: Although Mustafa Kemal Atatürk (1881-1938) was a national hero with his intrepid and enlightened attempts to establish modern Turkey from the remnants of Ottoman heritage, he had been suffering from lifelong "kidney disease" that appeared with intermittent flank pain and fever without an identified source. However, we think that this physical pain that he endured only increased his motivation to focus on his military and political aims. Methods & Results: In this historical review article, we have focused on his personal medical life and specifically his "kidneys" from the beginning of the complaint till his death through European medical and political history with geographic locations and speculated upon it via past, near past, and recent medical literature.

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ABTRACTWe aimed to assess the correlation between ISUP 2014 grades of needle biopsy (NB) and radical prostatectomy (RP) specimens and the parameters effecting this correlation. A total of 353 patients, who underwent a radical prostatectomy with diagnose of prostate cancer, were included in the study. Especially, the maximum percentage of core involved by cancer (MPCI) of upgraded group was significantly higher than those of correlated group and downgraded group.

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Article Synopsis
  • The study investigates histological differences in the prepuce of adults with primary distal hypospadias compared to healthy adults, focusing on microvessel and nerve density, as well as receptor density for hormones like androgen, estrogen, and progesterone.
  • Conducted from 2014 to 2019, it involved 28 participants: 18 with primary distal hypospadias and 10 healthy controls who underwent circumcision for social or religious purposes.
  • Findings reveal that the hypospadias group had increased microvascular density and inflammation, while hormone receptor density was similar, except that progesterone receptors were significantly lower in the hypospadias group compared to the controls.
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Aim: We aimed to investigate the predictor role of the systemic immune-inflammation index (SII) on Bacille Calmette-Guerin (BCG) response in patients with high-risk non-muscle invasive bladder cancer (NMIBC).

Methods: A total of 96 patients with high-risk NMIBC, who received intravesical BCG, were enrolled in the study. BCG responsive group (group 1) and BCG failure group (group 2) were compared in terms of demographic and pathological data, peripheral lymphocyte, neutrophil and platelet counts, neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), SII, recurrence-free survival (RFS) and progression-free survival (PFS).

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Aim: We evaluated the COVID-19 infection threat in patients receiving intravesical BCG therapy which has immunotherapeutic effects and is of vital importance in most of the individuals with high-risk non-muscle-invasive bladder cancer (NMIBC) and investigated the need for postponement of this therapy.

Methods: A total of 71 patients, who were diagnosed with high-risk NMIBC and on intravesical BCG treatment regularly (induction or maintenance), were enrolled in the study. The patients were classified into two groups depending on whether they were diagnosed with COVID-19 during the pandemic period or not.

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Aims: This study aims to analyse the novel Coronavirus disease- (COVID-19) related testicular pain in hospitalised patients because of COVID-19 and to review as an aetiological factor for epididymitis, orchitis or both.

Methods: A total of 91 patients were included in the study. A questionnaire was formed for the questioning of testicular pain or epididymo-orchitis in patients with COVID-19.

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Objective: In this study, we aimed to determine the predictive factor for additional treatment requirement in active surveillance (AS) for patients with low or very low-risk prostate cancer (PCa) and we investigated the effect of tumor burden by total core involvement rate in biopsy to predict of need for additional treatment.

Material And Methods: 107 patients with PCa in AS between 2005 and 2018 have been evaluated retrospectively. Groups were divided into two groups according to the need for additional treatment.

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Objective: We aimed to determine whether atherogenic dyslipidemia is associated with the disease and morbidity in our patients treated for Fournier's gangrene (FG).

Methods: Sixty-two patients who were treated with the diagnosis of FG at our center between 2012 and 2017 were retrospectively screened.

Results: The triglyceride values of the patients who required reconstructive surgery were statistically significantly higher than those of the patients for whom wound debridement and primary suturing was sufficient (p:0.

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Objective: To analyse the association of prostate cancer (PCa) Gleason score evaluated upon prostate biopsy with clinical PSA values, total and free testosterone (TT and FT, respectively) levels measured prior to biopsy.

Study Design: A descriptive study.

Place And Duration Of Study: Department of Urology, Sultan Abdulhamid Han Education and Research Hospital, from July to December 2019.

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Synopsis of recent research by authors named "Serkan Akan"

  • - Serkan Akan's recent research primarily focuses on urological topics, including the evaluation of diagnostic tools and the investigation of complications related to urological procedures, as demonstrated in his study on the reliability and validity of the Turkish version of a lower urinary tract dysfunction questionnaire and case reports on double J stent complications.
  • - His work also explores the intersection of urology and oncology, as seen in studies addressing factors influencing post-treatment fertility intention in testicular cancer patients and the association of serum carcinoembryonic antigen levels with bladder cancer metastasis.
  • - Additionally, Akan has investigated unique medical cases such as androgen receptor-positive penile acrochordon and Guillain-Barré syndrome following Bacillus Calmette-Guérin therapy, highlighting rare occurrences and their clinical implications.