Publications by authors named "Serik Ibrayev"

Prostate cancer (PCa) is the second most commonly diagnosed cancer, and the sixth most common killer among men worldwide (Aubry et al., 2013). This research was motivated by the fact that PCa screening continues to be a controversial topic in the Kazakh medical community.

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Article Synopsis
  • The study compares the effectiveness and cost-effectiveness of a triple therapy (peginterferon, ribavirin, and protease inhibitors) against a dual therapy (peginterferon and ribavirin) for treating chronic HCV in Kazakhstan.
  • A Markov model was utilized to evaluate long-term outcomes and costs, revealing that patients on triple therapy had better health outcomes and quality-adjusted life years (QALYs) than those on standard treatment.
  • The findings suggest that adding protease inhibitors to the standard treatment is cost-effective, with cost per QALY falling within acceptable thresholds based on Kazakhstan's economic standards.
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