Indices of nonspecific bronchial reactivity in severe asthma phenotype determination in schoolchildren.

Objective: Introduction: Severe asthma phenotype is characterized by peculiarities of inflammatory process in the airways and consequently hypersensitivity and bronchial lability. The aim: The study aims at determining the diagnostic value of bronchial lability indices in identifying severe bronchial asthma phenotype compared to the moderate variant of disease in schoolchildren.

Patients And Methods: Materials and methods: We formed two clinical groups of observation, the first clinical group included 57 children with severe asthma phenotype, the second clinical group included 65 patients with moderate disease course.