Surgical treatment of late aortic prosthetic valve endocarditis: 19 years' experience.

Aim Of The Study: We retrospectively analyzed the results of operations conducted for aortic prosthetic valve endocarditis in a single center over 19 years.

Material And Methods: From February 1992 to January 2011, we performed operations on 27 patients with aortic prosthetic valve endocarditis. Seventeen patients (63.

Protective effects of clopidogrel on oxidant damage in a rat model of acute ischemia.

Reperfusion injury is a consequence of inadequate energy supply and acidosis in ischemic tissues and a chain of events triggered by oxygen-derived free radicals released in response to exposure of oxygen. In this study, we aimed to assess the effects of clopidogrel, an antithrombotic agent, on experimental ischemia-reperfusion model in rats. The ischemia was performed by blockade of the circulation of right lower extremity at trochanter major level for 6 hours.