World Health Organization stated that "Cardiovascular diseases (CVDs) are the leading cause of death globally. Angiography is an important method in diagnostic of CVD. Standard-of-Care methods of angiography, such as X-Ray or CT- or MRI- angiography methods, being accurate and widely adopted in clinical practice, are bulky, expensive and energy in-efficient.
View Article and Find Full Text PDFMedical imaging has recently expanded into the dual- or multi-modality fusion of anatomical and functional imaging modalities. This significantly improves the diagnostic power while simultaneously increasing the cost of already expensive medical devices or investigations and decreasing their mobility. We are introducing a novel imaging concept of four-dimensional (4D) microwave tomographic (MWT) functional imaging: three dimensional (3D) in the spatial domain plus one dimensional (1D) in the time, functional dynamic domain.
View Article and Find Full Text PDFMicrowave tomography (MWT) is a novel imaging modality which might be applicable for non-invasive assessment of functional and pathological conditions of biological tissues. Imaging of the soft tissue of extremities is one of its potential applications. The feasibility of this technology for such applications was demonstrated earlier.
View Article and Find Full Text PDFPhilos Trans A Math Phys Eng Sci
August 2009
Microwave tomography (MWT) is an emerging biomedical imaging modality with great potential for non-invasive assessment of functional and pathological conditions of soft tissues. This paper presents a review of research results obtained by the author and his colleagues and focuses on various potential clinical applications of MWT. Most clinical applications of MWT imaging have complicated, nonlinear, high dielectric contrast inverse problems of three-dimensional diffraction tomography.
View Article and Find Full Text PDFIt is important to assess the viability of extremity soft tissues, as this component is often the determinant of the final outcome of fracture treatment. Microwave tomography (MWT) and sensing might be able to provide a fast and mobile assessment of such properties. MWT imaging of extremities possesses a complicated, nonlinear, high dielectric contrast inverse problem of diffraction tomography.
View Article and Find Full Text PDFWe have demonstrated previously that the dielectric properties of myocardium at microwave spectrum are a sensitive indicator of its blood content, ischemia, and infarction. The purpose of this study is to validate the feasibility of microwave tomography for detection of myocardial infarction based on the differences in dielectric properties between normal and infarcted tissues. Excised canine heats with two weeks myocardial infarction were imaged.
View Article and Find Full Text PDFWe studied dielectrical properties of canine myocardium during acute ischemia and hypoxia using dielectrical spectroscopy method at frequency spectrum from 100 kHz to 6 GHz. This study was conducted on a group of six canines with acute ischemia and seven canines with hypoxia. Hypoxia (10% for 30 min) decreases myocardial resistance (rho), while the dielectrical permittivity (epsilon') of the myocardial tissue remains statistically unchanged.
View Article and Find Full Text PDFThe purpose of this study was to construct a microwave tomographic system capable of conducting experiments with whole scale biological objects and to demonstrate the feasibility of microwave tomography for imaging such objects using a canine model. Experiments were conducted using a three-dimensional (3-D) microwave tomographic system with working chamber dimensions of 120 cm in diameter and 135 cm in height. The operating frequency was 0.
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