Publications by authors named "Sergio Moreno Fornes"
Objective: With HIV now a chronic condition and an aging population, understanding the evolving profiles of older people with HIV (PWH) is crucial. In this longitudinal study, we examined changes in epidemiological and mortality trends among aging PWH aged 60 and above from 1998 to 2021.
Design: The study constructed four retrospective cohorts based on our calendar periods, reflecting the changing epidemiology of HIV - 1998-2003, 2004-2008, 2009-2014, and 2015-2021.
Article Synopsis
- A study was conducted to create a risk score to predict loss to follow-up (LTFU) in patients living with HIV (PLWH) in Catalonia and the Balearic Islands.
- The study analyzed 6,661 PLWH and identified key factors contributing to LTFU, including age, nationality, drug use, viral load, and time since diagnosis.
- The results indicated that a significant portion of PLWH (28.8%) was at medium risk and 3.4% at high risk for LTFU, highlighting the need for targeted interventions to retain patients in HIV care.
Article Synopsis
- * The study analyzed cause of death using a modified protocol and found a significant decrease in all-cause mortality rates, dropping from 9.6 per 1000 person-years to 3.33. Major causes of death now include non-AIDS cancers, cardiovascular disease, and liver diseases.
- * Key predictors for both AIDS and non-AIDS mortality included factors like age, comorbidities, and ART adherence,
Objectives: To assess the effect of COVID-19 on the postacute risk of cardiovascular events (CVEs) among people with HIV (PWH).
Methods: Population-based matched cohort, including all PWH ≥16 years in the Catalan PISCIS HIV cohort. We estimated the incidence rate of the first CVE after COVID-19, analysed it a composite outcome (2020-2022).
Article Synopsis
- * PWH had higher booster vaccination rates (68.5% vs. 63.1%) than PWoH, particularly among those with advanced HIV profiles, like low CD4 counts.
- * The study identified factors such as prior SARS-CoV-2 diagnosis, migrant status, and socioeconomic challenges as barriers to primary vaccination for PWH, emphasizing the need for targeted interventions to enhance vaccine access and coverage.
Article Synopsis
- COVID-19 has a greater impact on migrants and ethnic minorities, including people with HIV, highlighting the need for detailed studies on their risks and outcomes.
- A study in Catalonia analyzed data from over 10,000 people with HIV, comparing COVID-19 testing, vaccination rates, and clinical outcomes between migrants and Spanish natives.
- Results showed migrants had lower testing and vaccination rates, faced higher hospitalization and ICU admission rates, but had similar COVID-19 diagnosis rates and mortality compared to non-migrants, indicating the necessity for targeted health policies.
Article Synopsis
- The COVID-19 pandemic led to a notable decrease in healthcare services usage among people living with HIV (PLWH) in Catalonia, particularly in HIV units, hospitals, and emergency departments.
- During the lockdown, overall medical visits decreased by 17.1%, with significant drops in specific healthcare facilities, while primary care visits remained relatively stable.
- CD4 and HIV RNA monitoring saw significant declines, emphasizing the need for better preparedness for future pandemics to maintain healthcare access for PLWH.
We aimed to evaluate the feasibility of an online self-sampling pilot intervention for HIV testing addressed to gay, bisexual, and other men who have sex with men (GBMSM) and trans women (TW) users of dating apps in Spain. The website https://www.testate.
View Article and Find Full Text PDFObjectives: People with HIV (PWH) have a higher cardiovascular risk than the general population. It remains unclear, however, whether the risk of cardiovascular disease (CVD) is higher in late HIV presenters (LP; CD4 ≤ 350 cells/μL at HIV diagnosis) compared to PWH diagnosed early. We aimed to assess the rates of incident cardiovascular events (CVEs) following ART initiation among LP compared to non-LP.
View Article and Find Full Text PDFIntroduction: People living with HIV who are lost to follow-up have a greater risk of health deterioration, mortality, and community transmission.
Objective: Our aim was to analyse both how rates of loss to follow-up (LTFU) changed between 2006 and 2020 and how the COVID-19 pandemic affected these rates in the PISCIS cohort study of Catalonia and the Balearic Islands.
Methods: We analysed socio-demographic and clinical characteristics of LTFU yearly and with adjusted odds ratios to assess the impact of these determinants on LTFU in 2020 (the year of COVID-19).
Objectives: To assess the clinical and immunovirological outcomes among naive patients with advanced HIV presentation starting an antiretroviral regimen in real-life settings.
Methods: This was a multicentre, prospective cohort study. We included all treatment-naive adults with advanced HIV disease (CD4+ T cell count < 200 cells/mm3or presence of an AIDS-defining illness) who started therapy between 2010 and 2020.
We aimed to assess the feasibility of TESTA'T COVID strategy among healthcare and education professionals.in Spain during the peak of the 6th wave caused by Omicron variant. Kits were ordered online and sent by mail, participants answered an online acceptability/usability survey and uploaded the picture of results.
View Article and Find Full Text PDFBackground: Late HIV diagnosis (i.e CD4≤350 cells/µL) is associated with poorer outcomes. However, determinants of long-term mortality and factors influencing immune recovery within the first years after antiretroviral treatment (ART) initiation are poorly defined.
View Article and Find Full Text PDFArticle Synopsis
- The article discusses the significance of epidemiological surveillance for HIV infection in Catalonia, aimed at monitoring incidence and planning interventions based on the data from the Integrated System of Epidemiological Surveillance of AIDS/HIV and Sexually Transmitted Infections (SIVES).
- A descriptive analysis was conducted on data from various SIVES sources, focusing on the cascade of HIV care as defined by the World Health Organization to present trends and outcomes in HIV management during the specified period.
- Results from 2012 to 2018 reveal a decrease in new diagnoses, with a majority of cases among men (especially men who have sex with men), and an estimate of 32,429 individuals living with HIV in 2018, where a high percentage were