Publications by authors named "Sergio Hofmeister de Almeida Martins Costa"
Article Synopsis
- Maternal deaths in low and middle-income countries, like Brazil, are often due to hypertensive issues, with preeclampsia being a major cause.
- Key factors contributing to these deaths include poor identification of high-risk women, inadequate prevention measures, and delays in diagnosis and treatment.
- To address this, the "4 P Rule" is suggested, emphasizing Adequate Prevention, Vigilant Prenatal Care, Timely Delivery, and Safe Postpartum to improve management and reduce mortality rates from preeclampsia.
Objective: To determine the profile of maternal deaths occurred in the period between 2000 and 2019 in the Hospital de Clínicas de Porto Alegre (HCPA, in the Portuguese acronym) and to compare it with maternal deaths between 1980 and 1999 in the same institution.
Methods: Retrospective study that analyzed 2,481 medical records of women between 10 and 49 years old who died between 2000 and 2018. The present study was approved by the Ethics Committee (CAAE 78021417600005327).
Pre-eclampsia: Universal Screening or Universal Prevention for Low and Middle-Income Settings?
Rev Bras Ginecol Obstet
January 2021
Pre-eclampsia (PE) is a severe disorder that affects up to 8% of all pregnancies and represents an important cause of maternal and perinatal morbidity and mortality. The screening of the disease is a subject of studies, but the complexity and uncertainties regarding its etiology make this objective a difficult task. In addition, the costs related to screening protocols, the heterogeneity of the most affected populations and the lack of highly effective prevention methods reduce the potential of current available algorithms for screening.
View Article and Find Full Text PDFPre-eclampsia is a multifactorial and multisystemic disease specific to gestation. It is classically diagnosed by the presence of hypertension associated with proteinuria manifested in a previously normotensive pregnant woman after the 20 week of gestation. Pre-eclampsia is also considered in the absence of proteinuria if there is target organ damage.
View Article and Find Full Text PDFThe associations of Cesarean delivery with offspring metabolic and immune-mediated diseases are believed to derive from lack of mother-to-newborn transmission of specific microbes at birth. Bifidobacterium spp., in particular, has been hypothesized to play a health-promoting role, yet little is known about how delivery mode modifies colonization of the newborn by this group of microbes.
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