Immune Thrombocytopenic Purpura Secondary to Cytomegalovirus (CMV) Infection: A Clinical Case.

Immune thrombocytopenic purpura (ITP) is an autoimmune condition characterized by a reduced platelet count due to enhanced peripheral destruction and impaired platelet production. While thrombocytopenia is a well-documented complication of various viral infections, cytomegalovirus (CMV), a member of the Herpesviridae family, is primarily associated with infections in immunocompromised patients and is rarely implicated in causing severe thrombocytopenia in immunocompetent patients. This article aims to highlight the importance of considering CMV as a significant etiological factor in ITP, particularly in cases of asymptomatic thrombocytopenia.

Physicochemical and functional properties of new sports drink with ricotta cheese whey and a brazilian passion fruit variety.

Unlabelled: The present study investigated the bioaccessibility of minerals, bioactive compounds, and sensory acceptance of isotonic beverages formulated with Ricotta cheese whey (RCW) and passion fruit cv. BRS Sertão Forte. Three formulations were developed: I1 with 50% RCW and 5% passion fruit pulp, I2 with 50% RCW and 8.

Xanthogranulomatous Pyelonephritis Presenting as a Psoas Abscess.

Xanthogranulomatous pyelonephritis (XGP) is a rare form of severe pyelonephritis. It is characterized by progressive parenchymal destruction caused by chronic urinary tract obstruction and infection, typically resulting in a non-functioning enlarged kidney. Its presentation with a psoas abscess is infrequent, and only a few cases are described in the literature.

Brazilian varieties of acerola (Malpighia emarginata DC.) produced under tropical semi-arid conditions: Bioactive phenolic compounds, sugars, organic acids, and antioxidant capacity.

Acerola fruit has gained prominence for its high nutraceutical value, associated with high levels of ascorbic acid and phenolic compounds. The objectives of this study were to analyze the chemistry composition and antioxidant capacity in seven Brazilian varieties of acerola. All acerola genotypes were harvested at the red ripe maturity stage, and the fruit were subjected to metabolite analyses by High-Performance Liquid Chromatography.

[Financing and management: the technical efficiency in public health expenditures of small-scale municipalities in the state of Santa Catarina].

In a context of budget constraints and fiscal austerity measures, the discussion of issues related to the efficient management of public resources is a major challenge. The scope of this study was to assess the technical efficiency of municipalities of the State of Santa Catarina in public health expenditures and its relationship with health management conditions in the years 2009 and 2015. In order to measure efficiency, the decision was made to use Data Envelopment Analysis.

Performance of new low-cost handheld NIR spectrometers for nondestructive analysis of umbu (Spondias tuberosa Arruda) quality.

The objective of this study was to evaluate the analytical performance of two new low-cost handheld NIR spectrometers for the determination of umbu fruit (Spondias tuberosa Arruda) quality. A third handheld spectrometer, representing a proven good performance for fruit quality analysis, was used as reference instrument. Multivariate calibration models were built using Partial Least Squares regression to determine dry matter (DM), soluble solids (SS), flesh firmness (FF) and skin color (SC).

Effect of Pseudocolor Filter in Micro-computed Tomography Images for Detection of Proximal and Occlusal Caries Lesions in Primary Molars.

Aim: This study aimed to evaluate the effect of pseudocolor filter in micro-computed tomography (CT) images for the detection of proximal and occlusal caries lesions in primary molars.

Materials And Methods: For this in vitro analysis, 26 extracted human primary teeth were scanned using a compact micro-CT device (Skyscan 1172, Bruker micro-CT, Kontich, Belgium) and the projection images were reconstructed into cross-sectional slices (NRecon v.1.

High loads of nano-hydroxyapatite/graphene nanoribbon composites guided bone regeneration using an osteoporotic animal model.

Background: It has been difficult to find bioactive compounds that can optimize bone repair therapy and adequate osseointegration for people with osteoporosis. The nano-hydroxyapatite (nHAp)/carbon nanotubes with graphene oxides, termed graphene nanoribbons (GNR) composites have emerged as promising materials/scaffolds for bone regeneration due to their bioactivity and osseointegration properties. Herein, we evaluated the action of nHAp/GNR composites (nHAp/GNR) to promote bone regeneration using an osteoporotic model.

Disassembly of the fruit cell wall by the ripening-associated polygalacturonase and expansin influences tomato cracking.

Fruit cracking is an important problem in horticultural crop production. Polygalacturonase (SlPG) and expansin (SlEXP1) proteins cooperatively disassemble the polysaccharide network of tomato fruit cell walls during ripening and thereby, enable softening. A Golden 2-like (GLK2) transcription factor, SlGLK2 regulates unripe fruit chloroplast development and results in elevated soluble solids and carotenoids in ripe fruit.

Cement AH Plus Adhesiveness Assessment Associated with Mineral Trioxide Aggregate in Different Proportions (Push-out Test).

Aim: The aim of the study is to evaluate the adhesiveness of the AH Plus plug cement, plus the mineral trioxide aggregate (MTA) in different proportions, through the push-out test.

Materials And Methods: The authors utilized fifty premolars with a single conduit, which were divided into five groups with 10 teeth. In group 1, the authors performed an obturation with AH Plus cement, group 2 was filled with AH Plus cement with 10% of MTA, group 3 was filled with AH Plus cement plus 20% MTA, group 4 was filled with AH Plus with 30% of MTA and group 5 filling was performed with the MTA Fillapex endodontic cement.

Carbon Nanomaterials for Treating Osteoporotic Vertebral Fractures.

Purpose Of Review: To identify the use of carbon nanomaterials in bone regeneration and present new data on the regenerative capacity of bone tissue in osteopenic rats treated with graphene nanoribbons (GNRs).

Recent Findings: The results show that the physical and chemical properties of the nanomaterials are suitable for the fabrication of scaffolds intended for bone regeneration. The in vitro tests suggested a non-toxicity of the GNRs as well as improved biocompatibility and bone mineralization activity.

Comparing the analytical performances of Micro-NIR and FT-NIR spectrometers in the evaluation of acerola fruit quality, using PLS and SVM regression algorithms.

The main goal of this study was to investigate the analytical performances of a state-of-the-art device, one of the smallest dispersion NIR spectrometers on the market (MicroNIR 1700), making a critical comparison with a benchtop FT-NIR spectrometer in the evaluation of the prediction accuracy. In particular, the aim of this study was to estimate in a non-destructive manner, titratable acidity and ascorbic acid content in acerola fruit during ripening, in a view of direct applicability in field of this new miniaturised handheld device. Acerola (Malpighia emarginata DC.

Frequency of the mesiopalatal canal in upper first permanent molars viewed through computed tomography.

The success of any endodontic therapy depends on factors such as correct diagnosis and prognosis. Unawareness or failure to locate additional canals, such as the mesiopalatal canal in the upper first molar, may lead to unsuccessful treatment. Hence, it is valid to consider all the resources available for locating this anatomic structure, e.

Rapid and non-destructive determination of quality parameters in the 'Tommy Atkins' mango using a novel handheld near infrared spectrometer.

The objective of this study was to evaluate the potential of a new handheld ultra-compact near infrared (NIR) spectrometer, based on the linear-variable filter (LVF) technology for rapid and non-destructive quality control analysis of the 'Tommy Atkins' mango. Multivariate calibration models were built using the Partial Least Squares (PLS) regression method to determine soluble solids (SS), dry matter (DM), titratable acidity (TA) and pulp firmness (PF). Different spectral pre-processing techniques were tested.

Analysis of Bone Repair and Inflammatory Process Caused by Simvastatin Combined With PLGA+HA+βTCP Scaffold.

Purpose: This study evaluated the tissue and inflammatory responses to the use of simvastatin and poly(lactic-co-glycolic acid) + hydroxyapatite + β-tricalcium phosphate (PLGA+HA+βTCP) scaffold for bone repair.

Materials And Methods: Two defects of 5 mm in diameter were made in the calvaria of rats, which were shared into the following 6 groups: naive, sham, vehicle, PLGA+HA+βTCP scaffold, simvastatin (4 mg/mL), and simvastatin with the scaffold. Tissue samples were collected at 1, 7, 15, 30, and 60 days after surgery.

The Ability of Dental Specialists to Distinguish Lateral Incisor Metal-Free From Porcelain-Fused-to-Metal Implant Supported Crowns.

The objective of this study was to evaluate the ability of dental specialists to distinguish lateral incisor metal-free from porcelain-fused-to-metal implant supported crowns in the anterior region. Five single-tooth implants in the maxillary lateral incisor region were restored with two types of implant-supported crowns (porcelain-fused-to-metal and metal-free). Photographs were presented to 20 evaluators.

A transcriptome approach towards understanding the development of ripening capacity in 'Bartlett' pears (Pyrus communis L.).

Background: The capacity of European pear fruit (Pyrus communis L.) to ripen after harvest develops during the final stages of growth on the tree. The objective of this study was to characterize changes in 'Bartlett' pear fruit physico-chemical properties and transcription profiles during fruit maturation leading to attainment of ripening capacity.

Model for the evaluation of drug-dispensing services in primary health care.

Objective: To develop a model for evaluating the efficacy of drug-dispensing service in primary health care.

Methods: An efficacy criterion was adopted to determine the level of achievement of the service objectives. The evaluation model was developed on the basis of a literature search and discussions with experts.

[Evaluation of municipal management of the Brazilian National School Nutrition Program in the largest cities of Santa Catarina State, Brazil].

This article reports on an evaluative study of municipal management of the Brazilian National School Nutrition Program in the largest cities in Santa Catarina State, Brazil. The matrix of indicators included two dimensions: political-organizational, with the sub-dimensions resources, inter-sector action, and social control, and operational-technical, organized in nutritional and feeding efficacy, nutritional monitoring, and educational activities for a healthy diet. A total of 22 indicators were determined, and data were collected through interviews with nutritionists.

Microbial reduction by two chemical-mechanical protocols in primary teeth with pulp necrosis and periradicular lesion - an in vivo study.

The objective of this study was to determine the efficacy of chemical-mechanical procedures of two endodontic protocols for septic content reduction of root canals from primary teeth with pulp necrosis and periradicular lesion. Twenty-four primary root canals with pulp necrosis and periradicular lesion were divided into two treatment groups (n=12): multiple-visit and single-visit protocols. Samples were collected using sterile paper points before and after endodontic cleaning followed by microbiological identification through checkerboard DNA-DNA hybridization.

[The development of evaluation capacity in primary healthcare management: a case study in Santa Catarina State, Brazil, 2008-2011].

This article analyzes evaluation capacity-building based on the case study of a State Health Secretariat participating in the Project to Strengthen the Technical Capacity of State Health Secretariats in Monitoring and Evaluating Primary Healthcare. The case study adopted a mixed design with information from documents, semi-structured interviews, and evaluation of primary care by the State Health Secretariat in 2008-2011. Process analysis was used to identify the logical events that contributed to evaluation capacity-building, with two categories: evaluation capacity-building events and events for building organizational structure.

Microbial profile of root canals of primary teeth with pulp necrosis and periradicular lesion.

Purpose: The purpose of this study was to assess the microbial content of root canals of human primary teeth with pulp necrosis and periradicular lesion.

Methods: Microbial samples were collected from 24 canals of children treated at a pediatric dentistry clinic. Microbiological identification was performed using checker-board DNA-DNA hybridization for 40 different bacteria.

The Linear Programming to evaluate the performance of Oral Health in Primary Care.

Objective: To show the use of Linear Programming to evaluate the performance of Oral Health in Primary Care.

Methods: This study used data from 19 municipalities of Santa Catarina city that participated of the state evaluation in 2009 and have more than 50,000 habitants. A total of 40 indicators were evaluated, calculated using the Microsoft Excel 2007, and converted to the interval [0, 1] in ascending order (one indicating the best situation and zero indicating the worst situation).

Role of pectin methylesterases in cellular calcium distribution and blossom-end rot development in tomato fruit.

Blossom-end rot (BER) in tomato fruit (Solanum lycopersicum) is believed to be a calcium (Ca²⁺) deficiency disorder, but the mechanisms involved in its development are poorly understood. Our hypothesis is that high expression of pectin methylesterases (PMEs) increases Ca²⁺ bound to the cell wall, subsequently decreasing Ca²⁺ available for other cellular functions and thereby increasing fruit susceptibility to BER. The objectives of this study were to evaluate the effect of PME expression, and amount of esterified pectins and Ca²⁺ bound to the cell wall on BER development in tomato fruit.

Evaluation of actions concerning systemic arterial hypertension in primary healthcare.

Objective: To evaluate the efficiency of the Family Health Strategy in actions related to hypertension.

Methods: Evaluative, cross-sectional quantitative research based on secondary data of 66 small municipalities located in the state of Santa Catarina, Southern Brazil, with maximum potential coverage of 100% by the Family Health Strategy in 2007. Input indicators, products and results were evaluated.