Publications by authors named "Sergio Chibute"
Article Synopsis
- The study examined the prevalence of pyruvate kinase (PK) deficiency in four malaria-endemic African countries, focusing on its association with malaria protection.
- Researchers found that 4.1% of individuals in Maputo had reduced PK activity, with a high frequency of the rare G829A mutation in the PKLR gene.
- Although the variant was more common in individuals with uncomplicated malaria, no significant link was established between PK deficiency or mutation frequency and malaria infection outcomes.
