Publications by authors named "Sergi Ramirez-Martinez"
Article Synopsis
- Cerebral amyloid angiopathy (CAA) is linked to small vessel disease (SVD) and can be assessed through specific MRI markers, influencing brain connectivity.
- A study with 73 CAA patients found a significant inverse relationship between the total SVD MRI score and overall brain connectivity, indicating that more SVD-related injury correlates with reduced connectivity.
- Key SVD markers such as cortical superficial siderosis and moderate-severe white matter hyperintensities were specifically associated with declines in global network efficiency.
Objective: To evaluate the local effect of small asymptomatic infarctions detected by diffusion-weighted imaging (DWI) on white matter microstructure using longitudinal structural and diffusion tensor imaging (DTI).
Methods: Nine acute to subacute DWI lesions were identified in 6 subjects with probable cerebral amyloid angiopathy who had undergone high-resolution MRI both before and after DWI lesion detection. Regions of interest (ROIs) corresponding to the site of the DWI lesion (lesion ROI) and corresponding site in the nonlesioned contralateral hemisphere (control ROI) were coregistered to the pre- and postlesional scans.