Publications by authors named "Sergi Gavilan"
Background: In yaws-endemic areas, children with Treponema pallidum subsp. pertenue infection may suffer recurrent episodes due to either reinfection or relapse. However, the possibility of infection with other cutaneous ulcer causative agents and difficulties in interpreting standard laboratory results challenges the estimation of yaws recurrence rates.
View Article and Find Full Text PDFBackground: Current strategies for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited to nonpharmacologic interventions. Hydroxychloroquine has been proposed as a postexposure therapy to prevent coronavirus disease 2019 (Covid-19), but definitive evidence is lacking.
Methods: We conducted an open-label, cluster-randomized trial involving asymptomatic contacts of patients with polymerase-chain-reaction (PCR)-confirmed Covid-19 in Catalonia, Spain.
Background: No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be efficacious for outpatients with COVID-19.
Methods: Multicenter open-label, randomized, controlled trial conducted in Catalonia, Spain, between 17 March and 26 May 2020.
Article Synopsis
- Haemophilus ducreyi (HD) and Treponema pallidum subspecies pertenue (TP) are key causes of skin ulcers in tropical regions, and azithromycin may effectively treat these infections.
- A study on Lihir Island tested the efficacy of a single oral dose of azithromycin (30 mg/kg) on patients with skin ulcers, analyzing their healing rates based on PCR results for HD and TP.
- Results showed high healing rates at 14 days post-treatment, particularly in the HD group, supporting the use of azithromycin for managing cutaneous ulcers and influencing public health approaches in tropical areas.