Development and validation of the HPLC-DAD method for the quantification of 16 synthetic dyes in various foods and the use of liquid anion exchange extraction for qualitative expression determination.

Synthetic dyes can cause many health problems, and their use as food additives is rigorously regulated worldwide. Two methods for the determination of synthetic dyes in food are described in this article. The visual qualitative expression method was based on the extraction of synthetic dyes using a liquid anion exchanger (0.