Publications by authors named "Sergey B Landa"

Article Synopsis
  • Extracellular vesicles (EVs) are membrane-bound structures derived from cells that facilitate communication and transport various biological materials like proteins and RNAs between cells.
  • Adipose tissue EVs are linked to regulating metabolism and inflammation, playing a role in obesity-related conditions, such as insulin resistance and type 2 diabetes mellitus (T2DM).
  • This study characterizes EVs from visceral and subcutaneous fat in obese T2DM patients, revealing distinct morphological features and compositions that suggest altered EV production in these conditions compared to control groups.
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A mirror-symmetry motif was discovered in the N-terminus of the influenza virus PB1 protein. Structure of peptide comprised of the corresponding part of PB1 (amino acid residues 6-25) was investigated by circular dichroism and in silico modeling. We found that peptide PB1 (6-25) in solution assumes beta-hairpin conformation.

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