Publications by authors named "Sergey A Mironov"

Cardiorespiratory interactions are important, both for understanding the fundamental processes of functioning of the human body and for development of methods for diagnostics of various pathologies. The properties of cardiorespiratory interaction are determined by the processes of autonomic control of blood circulation, which are modulated by the higher nervous activity. We study the directional couplings between the respiration and the process of parasympathetic control of the heart rate in the awake state and different stages of sleep in 96 healthy subjects from different age groups.

View Article and Find Full Text PDF
Article Synopsis
  • A mathematical model for autonomic control of the cardiovascular system includes two self-exciting loops regulating heart rate and blood vessel tone based on baroreceptor activity.
  • The model analyzes how a healthy cardiovascular system adapts during a passive head-up tilt test, using computer simulations to track variables that are hard to measure directly, like noradrenaline concentration and blood pressure.
  • Results show the model's predictions align closely with experimental data from 50 healthy individuals, especially focusing on low-frequency oscillations in heart rate and blood pressure synchronization.
View Article and Find Full Text PDF

We studied the properties of low-frequency (LF) heart rate variability (HRV) and photoplethysmographic waveform variability (PPGV) and their interaction under conditions where the hemodynamic connection between them is obviously absent, as well as the LF regulation of PPGV in the absence of heart function. The parameters of HRV and finger PPGV were evaluated in 10 patients during cardiac surgery under cardiopulmonary bypass (on-pump cardiac surgery) with or without cardioplegia. The following spectral indices of PPGV and HRV were ertimated: the total spectral power (TP), the high-frequency (HF) and the LF ranges of TP in percents (HF% and LF%), and the LF/HF ratio.

View Article and Find Full Text PDF