Publications by authors named "Sergei Surkov"

Background: More than two years of the COVID-19 pandemic has changed lives of people around the world and had a profound impact on the field of sports. This has resulted in decreased physical activity (PA) and changes in mental health. The goal was to assess self-reported physical activity, life satisfaction, perceived stress, choice of coping strategies and their correlations among student athletes from two neighboring countries facing different anti-pandemic strategies.

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The COVID-19 restrictions in Belarus turned out to be less stringent than those of its neighboring countries. Objective: We aimed to evaluate physical activity, life satisfaction, perception of stress, choice of coping strategies and their correlations among Belarusian students. An anonymous Internet survey was conducted among 1769 students studying at the faculties of physical culture (415), pedagogical (737), and medical (617) universities.

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In this study, we checked whether HSP70 preparations of different origins are able to protect model animals (rats) from endotoxic shock and modify the response of myeloid cells to lipopolysaccharide (LPS) challenge. It was shown that HSP70 preparations can effectively protect organisms from endotoxic shock by strongly decreasing mortality and restoring both homeostasis and various hemodynamic characteristics. At the cellular level, HSP70 preparations significantly inhibit LPS-induced reactive oxygen species production in various myeloid cells and decrease NO expression in macrophages, which is enhanced after LPS priming.

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