Publications by authors named "Sergei Mikhailov"
Article Synopsis
- - The study emphasizes the importance of high-resolution annual forest growth maps, using tree-ring width (TRW) data, to better understand forest carbon sequestration and the impact of climate change and drought on forest ecosystems.
- - By integrating high-resolution Earth observation data with climate and topography information, the researchers found that species-specific models could explain over 52% of variance in tree growth, enhancing the accuracy of growth predictions compared to using just climate and elevation data.
- - The research successfully generated a map of annual TRW for 2021, demonstrating that combining different data sources can lead to more effective models for forest growth, while also identifying areas where predictions may be less reliable, particularly in climate marginal zones.
We demonstrate distributed optical fiber-based pressure measurements with sub-bar pressure resolution and 1 m spatial resolution over a ∼100 m distance using a phase-sensitive optical time-domain reflectometry technique. To do so, we have designed a novel highly birefringent microstructured optical fiber that features a high pressure to temperature sensitivity ratio, a high birefringence and a mode field diameter that is comparable to that of conventional step-index single mode fibers. Our experiments with two fibers fabricated according to the design confirm the high polarimetric pressure sensitivities (-62.
View Article and Find Full Text PDFIn this paper, a long-distance distributed pressure sensing system based on a special fiber and using frequency-scanned phase-sensitive optical time-domain reflectometry is proposed. The fiber shows high pressure sensitivity (159 MHz/bar) and low loss (3 dB/km) owing to its simple structure made of two large air holes in the cladding. The pressure response of the two orthogonal polarization axes of the fiber is explored distinctively.
View Article and Find Full Text PDFIntroduction: Performance status (PS) 2 patients with non-small cell lung cancer (NSCLC) experience more toxicity, lower response rates, and shorter survival times than healthier patients treated with standard chemotherapy. Paclitaxel poliglumex (PPX), a macromolecule drug conjugate of paclitaxel and polyglutamic acid, reduces systemic exposure to peak concentrations of free paclitaxel and may lead to increased concentrations in tumors due to enhanced vascular permeability.
Methods: Chemotherapy-naive PS 2 patients with advanced NSCLC were randomized to receive carboplatin (area under the curve = 6) and either PPX (210 mg/m/10 min without routine steroid premedication) or paclitaxel (225 mg/m/3 h with standard premedication) every 3 weeks.