Porous Zirconia/Magnesia Ceramics Support Osteogenic Potential In Vitro.

Porous zirconia (ZrO), magnesia (MgO) and zirconia/magnesia (ZrO/MgO) ceramics were synthesised by sintering and designated as ZrO(100), ZrO(75)MgO(25), ZrO(50)MgO(50), ZrO(25)MgO(75), MgO(100) based on their composition. The ceramic samples were characterised by means of scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy and atomic absorption spectrometry to explore the incorporation of Mg atoms into the zirconia lattice. The resulting porosity of the samples was calculated based on the composition and density.

Preparation of Zr(Mo,W)O with a larger negative thermal expansion by controlling the thermal decomposition of Zr(Mo,W)(OH,Cl)∙2HO.

Solid solutions of Zr(Mo,W)O(OH,Cl)∙2HO with a preset ratio of components were prepared by a hydrothermal method. The chemical composition of the solutions was determined by energy dispersive X-ray spectroscopy (EDX). For all the samples of ZrMoWO(OH,Cl)∙2HO (x = 0.

Effect of Porosity of Alumina and Zirconia Ceramics toward Pre-Osteoblast Response.

It is acknowledged that cellular responses are highly affected by biomaterial porosity. The investigation of this effect is important for the development of implanted biomaterials that integrate with bone tissue. Zirconia and alumina ceramics exhibit outstanding mechanical properties and are among the most popular implant materials used in orthopedics, but few data exist regarding the effect of porosity on cellular responses to these materials.

Proliferation and osteogenic response of MC3T3-E1 pre-osteoblastic cells on porous zirconia ceramics stabilized with magnesia or yttria.

Dense zirconia ceramics are used in bone applications due to their mechanical strength and biocompatibility, but lack osseointegration. A porous interface in contact with bone tissue may lead to better bone bonding but the biological properties of porous zirconia are not widely explored. The present study focuses on the manufacturing of an yttria- (YSZ) and a magnesia-stabilized (MgSZ) porous zirconia, and on their in vitro biological investigation.