VEGF Detection via Impedance Spectroscopy on Surface Functionalized Interdigitated Biosensor.

Vascular endothelial growth factor (VEGF), a clinically important biomarker, often plays a key role in angiogenesis, would healing, tumor growth, lung development, and in retinal diseases. Hence, detecting and quantifying VEGF is deemed medically important in clinical diagnosis for many diseases. In this report, a simple yet highly cost-effective platform was proposed for VEGF protein detection using commercially available interdigitated sensors that are surface modified to present DNA optimally for VEGF capture.

A Novel Method for Baroreflex Sensitivity Estimation Using Modulated Gaussian Filter.

The evaluation of baroreflex sensitivity (BRS) has proven to be critical for medical applications. The use of indices by spectral methods has been the most popular approach to BRS estimation. Recently, an algorithm termed Gaussian average filtering decomposition (GAFD) has been proposed to serve the same purpose.

Sonochemical Reaction of Bifunctional Molecules on Silicon (111) Hydride Surface.

While the sonochemical grafting of molecules on silicon hydride surface to form stable Si-C bond via hydrosilylation has been previously described, the susceptibility towards nucleophilic functional groups during the sonochemical reaction process remains unclear. In this work, a competitive study between a well-established thermal reaction and sonochemical reaction of nucleophilic molecules (cyclopropylamine and 3-Butyn-1-ol) was performed on -type silicon hydride (111) surfaces. The nature of surface grafting from these reactions was examined through contact angle measurements, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM).