Publications by authors named "Serena Vilasi"
Article Synopsis
- Merkel cell carcinoma (MCC) and small cell lung cancer (SCLC) can look similar under a microscope, complicating their diagnosis and requiring specific tests to tell them apart.* -
- Current immunohistochemistry markers like cytokeratin 20 (CK20) and thyroid transcription factor 1 (TTF-1) are commonly used, but have limitations in sensitivity and specificity.* -
- New candidate markers, ATOH1 and TFAP2B for MCC, and CEACAM6 for SCLC, show high specificity and sensitivity in immunostaining, suggesting their potential in improving diagnostic accuracy.*
Importance: Racial and ethnic differences in skin cancer outcomes are understudied. Delineating these differences in Merkel cell carcinoma (MCC) is needed to better understand this rare disease.
Objective: To determine how MCC presentation and outcomes differ across racial and ethnic groups.
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer that predominantly impacts White patients. Overall incidence and the proportion of minority patients with MCC are both rising. In the more common skin cancer, melanoma, racial disparities are well-documented in stage at presentation and patient survival.
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