Crohn's disease after surgery: Changes in post-operative management strategies over time and their impact on long-term re-operation rate-A retrospective multicentre real-world study.

Background: Few data are available addressing the impact of post-operative management of Crohn's disease (CD) on long-term clinical course.

Aim: To assess the evolution of post-operative management strategies over the last 40 years and their impact on the re-operation rate of CD.

Methods: We included 657 patients with CD who had undergone their first radical ileo-caecal resection between 1980 and 2020.