Assessment of response to chemotherapy in pancreatic ductal adenocarcinoma: Comparison between diffusion-weighted MR quantitative parameters and RECIST.

Purpose: To prospectively assess chemotherapy-induced changes in pancreatic ductal adenocarcinoma (PDA) with diffusion-weighted (DW)-MR quantitative metrics, including apparent diffusion coefficient (ADC) and histogram-derived parameters, compared with RECIST 1.1.

Methods: 24 patients underwent DW-MR at baseline, week-2 and week-8 after chemotherapy initiation.

Impact of multiparametric magnetic resonance imaging on risk group assessment of patients with prostate cancer addressed to external beam radiation therapy.

Purpose: To investigate the impact of multiparametric magnetic resonance imaging (mpMRI) on risk group assessment of patients with prostate cancer (PCa) initially addressed to external beam radiation therapy (EBRT).

Materials And Methods: We prospectively performed mpMRI (3.0Tsystem) in 44 patients addressed to EBRT, using a multiparametric protocol (high-resolution multiplanar T2-weighted, diffusion-weighted and dynamic contrast-enhanced imaging).

Differentiating small (≤1 cm) focal liver lesions as metastases or cysts by means of computed tomography: a case-study to illustrate a fuzzy logic-based method to assess the impact of diagnostic confidence on radiological diagnosis.

Purpose: To quantify the impact of diagnostic confidence on radiological diagnosis with a fuzzy logic-based method.

Materials And Methods: Twenty-two oncologic patients with 20 cysts and 30 metastases ≤1 cm in size found at 64-row computed tomography were included. Two readers (R1/R2) expressed diagnoses as a subjective level of confidence P(d) in malignancy within the interval [0,1] rather than on a "crisp" basis (malignant/benign); confidence in benignancy was 1 - p(d).

Does diffusion-weighted imaging add diagnostic confidence in discriminating between benign and malignant solid focal liver lesions?

We investigated whether diffusion-weighted Imaging (DWI) adds diagnostic confidence in assessing focal liver lesions (FLLs). By reviewing FLLs without and with DWI at 1.5 T, two radiologists scored the confidence in diagnosing benignancy/malignancy (confidence score), and DWI usefulness (usefulness score).