Publications by authors named "Serena Maione"
Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention has been given to its role in adipose tissue. We report here that levels of PKP2 steadily increase during fat cell differentiation, and are compromised if adipocytes are exposed to a pro-inflammatory milieu.
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- Some organisms, called psychrophiles, have special enzymes that help them work well in very cold temperatures.
- Scientists studied a specific enzyme from a cold-loving bacteria called Marinomonas ef1 and found it can still work even at warmer temperatures, showing it's really tough.
- They discovered the enzyme has a unique structure that helps it do its job effectively in the cold, which challenges what we thought we knew about how cold enzymes usually behave.