Superior vena cava filter placement over existing central venous lines: Is line removal necessary?

Objectives: To evaluate the technical feasibility and clinical safety of superior vena cava (SVC) filter placement over preexisting central venous lines (CVLs) in 23 patients who had upper extremity deep venous thrombosis with contraindications to anticoagulation.

Methods: A retrospective review of the images and electronic medical records of 23 patients from 2008 to 2018 with SVC filters placed over an existing central venous line was performed in a single tertiary medical center. Twenty-one filters were placed over smaller lines (<8 Fr), and two were placed over hemodialysis catheters.

Management of cardiac tamponade during catheter-directed thrombolysis of saddle pulmonary embolism: A clinical dilemma.

Catheter-directed thrombolysis (CDT) for the treatment of acute pulmonary embolism (PE) has gained popularity in recent years, but potential complications during the procedure and their management are not frequently discussed in the literature. In this case report, we describe the clinical dilemma regarding the postoperative anticoagulation management of a 60-year-old male who developed cardiac perforation during a CDT of an acute saddle PE. Early resumption of systemic heparin in such cases may help in clot resolution; however, it can worsen the hemopericardium.

Effects of Citalopram on Sutural and Calvarial Cell Processes.

The use of selective serotonin reuptake inhibitors (SSRIs) for the treatment of depression during pregnancy is suggested to increase the incidence of craniofacial abnormalities including craniosynostosis. Little is known about this mechanism, however based on previous data we propose a mechanism that affects cell cycle. Excessive proliferation, and reduction in apoptosis may lead to hyperplasia within the suture that may allow for differentiation, bony infiltration, and fusion.