Publications by authors named "Seray Dizlek"
Microsatellite instability is a common finding in multiple myeloma.
Clin Lymphoma Myeloma
October 2009
Article Synopsis
- Microsatellite instability (MSI) is caused by DNA replication errors, which can be corrected by mismatch repair (MMR) genes, making its detection indicative of MMR gene disorder.
- In a study of 26 newly diagnosed multiple myeloma patients, 54% showed MSI in the immunoglobulin heavy chain gene, though no significant links were found between MSI and clinical stages or multiple myeloma subtypes.
- The findings suggest that genomic instability in heavy-chain multiple myeloma may be common and potentially important for understanding the disease's development.
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation, with a reported incidence between 0.8% to 32%. Herein we retrospectively analyzed the patients who diagnosed as PTLD in Akdeniz University.
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