Publications by authors named "Serati L"

Article Synopsis
  • About 0.5-1% of women of childbearing age have anti-Ro/SSA and anti-La/SSB antibodies, potentially leading to Neonatal Lupus, primarily manifesting as complete heart block (AVB) in fetuses.
  • The study aims to assess the effectiveness of home monitoring of fetal heart rates using a handheld device in pregnant women with these antibodies and to see if early treatment can help.
  • Currently, patients are being recruited across 11 Italian centers for a prospective observational study, with regular monitoring and check-ups to track maternal and fetal health outcomes.
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Anemia during acute inflammation is not well described in the literature. We aimed to study whether patients develop a transient hemoglobin decrease during an acute attack of recurrent pericarditis. We retrospectively analyzed patients with recurrent pericarditis.

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Recurrent pericarditis, an inflammatory syndrome with a pathogenesis not fully elucidated, often presents diagnostic challenges. This study aims to assess the correlation of D-Dimer (D-D) and procalcitonin (PCT) levels with clinical, laboratory and imaging features in recurrent idiopathic pericarditis. We analyzed 412 patients with idiopathic recurrent pericarditis from 2019 to 2023 in our referral center.

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Article Synopsis
  • Pericardial effusion is common in pregnant women and is usually benign, resolving naturally after delivery without treatment.
  • Acute pericarditis may require medical therapy during pregnancy, while other serious conditions like cardiac tamponade are rare.
  • Pre-pregnancy counseling is crucial for women with recurrent pericarditis to plan during stable periods, and certain medications are safe to use throughout pregnancy and breastfeeding.
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This review summarizes the currently available evidence on the management of acute and recurrent pericarditis during pregnancy, focusing on the safety of diagnostic procedures and treatment options for the mother and fetus. Family planning should be addressed in women with recurrent pericarditis of reproductive age and adjustment of therapy should be considered before a planned pregnancy. The treatment of pericarditis in pregnancy is similar to that for non-pregnant women but considers current knowledge on drug safety during pregnancy and lactation.

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Anti-Ro/SSA antibodies are associated with a risk of 1-2 % to develop complete atrioventricular block (AVB) in fetuses of positive mothers. Complete AVB is irreversible, but studies suggest that anti-inflammatory treatment during the transition period from a normal fetal heart rate (FHR) to an AVB might stop this progression and restore sinus rhythm. The most efficient method for diagnostic evaluation of this arrhythmia is the pulsed-Doppler fetal echocardiography.

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