Statins and hip fracture prevention--a population based cohort study in women.

Objective: To study the association of long-term statin use and the risk of low-energy hip fractures in middle-aged and elderly women.

Design: A register-based cohort study.

Setting: Finland.

[Electronic patient record in the monitoring of blood pressure of the population].

The implementation of the Finnish Current Care guidelines has been assessed mainly by questionnaire surveys. Methods for utilizing information accumulating into the electronic patient record were developed in a community health center. A register was created that stored 204573 blood pressure readings from 39570 patients.

Statin adherence and the risk of major coronary events in patients with diabetes: a nested case-control study.

Aims: To evaluate whether good statin adherence is associated with a reduced incidence of major coronary events (MCEs) among diabetic patients with and without coronary heart disease (CHD).

Methods: Using data derived by linkage of nationwide health databases in Finland, we conducted a nested case-control analysis of 3513 cases with an MCE, a composite of acute myocardial infarction and/or coronary revascularization, and 20,090 matched controls identified from a cohort of 60,677 statin initiators with diabetes. Cases and controls were matched according to gender, time of cohort entry and duration of follow-up and further classified to two risk groups according to the presence of CHD at statin initiation.

Long-term persistence with statin therapy: a nationwide register study in Finland.

Background: Preventive statin therapy is often recommended as lifelong treatment.

Objective: The aim of this study was to analyze persistence with statin therapy over a decade of use and to identify factors associated with its discontinuation.

Methods: Persistence with therapy among new users of statins in 1995 was followed up until December 31, 2005, in Finland using the nationwide drug reimbursement register.