Publications by authors named "Sephora Belo"
Article Synopsis
- The study aimed to assess how a clinical pharmacist's consultation affects the decision of patients with inflammatory rheumatic diseases to switch to biosimilars compared to those who did not receive this consultation.
- It involved analyzing 141 adult patients, revealing that those who had a consultation were more likely to switch to biosimilars (69.4% vs 41.1%).
- Although there was a good initial switch rate, retention of patients on biosimilars after one year was slightly lower in the intervention group (72.5% vs 81.3%), indicating the need for further research on the long-term effects of pharmacist consultations.
Pentobarbital is a sedative agent to limit children motion during computed tomography or magnetic resonance imaging (MRI) and ensures the successful completion of the imaging procedure. However, data on rectal drug formulation and its stability in practice are not available. The aim of this study was to formulate and evaluate the stability of a ready-to-use rectal pentobarbital gel.
View Article and Find Full Text PDFTherapeutic drug monitoring of antiepileptic drugs is widely practiced to achieve optimal efficacy and avoid adverse side effects. We describe an ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC/MS/MS) method developed for the monitoring of four frequently prescribed antiepileptic drugs - lamotrigine, levetiracetam, oxcarbazepine and topiramate. The main pharmacologically active metabolite of oxcarbazepine (mono-hydroxy-derivative metabolite, MHD) was also quantified.
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