Publications by authors named "Seonju Yi"

Background: The long-term mortality and morbidity of patients with severe fever with thrombocytopenia syndrome (SFTS) remain unclear.

Methods: This retrospective cohort study was conducted using the National Health Insurance Service dataset on hospitalized patients with SFTS aged ≥20 years between 2016 and 2021 (n = 1,217). Each SFTS case was matched with three controls hospitalized for non-SFTS-related diseases using propensity score matching.

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  • A study in South Korea analyzed the risk of reinfection for COVID-19 among residents from January to August 2022.
  • Children aged 5-11 years and 12-17 years were found to have a higher risk of reinfection, with adjusted hazard ratios of 2.20 and 2.00, respectively.
  • Receiving a 3-dose COVID-19 vaccination significantly reduced the risk of reinfection, with an adjusted hazard ratio of 0.20.
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  • A study evaluated the effectiveness of a fourth mRNA COVID-19 vaccine dose in people aged 60 and older in Korea during the Omicron BA.2 and BA.5 variants.
  • The effectiveness against severe infections was found to be 67.7% within the first 31-60 days after the booster.
  • By 61-90 days, the effectiveness slightly decreased to 62.1%, indicating ongoing protection but reduced efficacy over time.
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  • Data from Korea during the COVID-19 delta and omicron waves shows that individuals who received three vaccine doses have a significantly lower risk of severe infection (aOR, 0.05-0.08).
  • The study found that the risk of death from COVID-19 decreased in the omicron period compared to the earlier delta period (aOR, 0.75).
  • These findings suggest that vaccination, particularly with three doses, is effective in reducing both severe illness and mortality from COVID-19.
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  • * Analysis of the national COVID-19 registry revealed that 24.4% had both vaccination and infection, while nearly 10% of the population had no immunity; children were particularly affected with almost half lacking immunity.
  • * The findings highlight a significant gap in immunity levels, especially in children, suggesting the need for strategic vaccine policies to enhance national health measures.
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  • Researchers assessed the impact of a second mRNA COVID-19 booster on infection risks in immunocompromised individuals and long-term care facility residents in South Korea from February to May 2022.
  • Out of nearly 1 million eligible participants, 75.7% received a first booster while only 24.3% got a second booster dose.
  • Results showed that the second booster significantly improved protection against all infections (22.28% effectiveness), critical infections (56.95%), and deaths (62.96%) when compared to just having the first booster.
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Objectives: It is crucial to establish the characteristics of coronavirus disease 2019 (COVID-19) outbreaks at army training centers to develop preventive measures. Therefore, this study aimed to determine the COVID-19 transmission patterns and risk factors in a sequence of outbreaks at an army training center from June to August 2021.

Methods: This study included 1,324 trainees at an army training center where outbreaks occurred from June to August 2021.

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  • A study was conducted using data from South Korea to analyze SARS-CoV-2 reinfection rates from January 2020 to April 2022, involving over 16 million confirmed cases.
  • The analysis showed a total of 55,841 possible reinfections, with reinfection rates increasing significantly during the Delta (128.0 per 100,000) and Omicron (355.1 per 100,000) variants compared to the Pre-Delta period (6.0 per 100,000).
  • Individuals with one vaccine dose had the highest reinfection rate, suggesting that new variants played a major role in the increase of reinfections.
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  • The study evaluates the effectiveness of four COVID-19 vaccines in South Korea, focusing on their ability to prevent infections and severe outcomes.
  • It uses a large database linking national health data to assess infection rates and vaccine effectiveness, showing that fully vaccinated individuals had a significantly lower infection rate compared to unvaccinated ones.
  • Results indicate high effectiveness against severe disease (93%) and death (95%), with a substantial number of infections and deaths averted due to the vaccination campaign, although the study notes a lower-than-expected protection against infections.
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  • A nationwide study in South Korea investigated the rates of breakthrough COVID-19 infections among people vaccinated with four different vaccines.
  • The study found that the Janssen vaccine had the highest breakthrough infection rate at 42.6 cases per 100,000 population per month.
  • In comparison, AstraZeneca, Pfizer-BioNTech, and Moderna had lower rates of 21.7, 8.5, and 1.8 cases per 100,000 population, respectively.
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  • - Starting July 19, 2021, South Korea vaccinated all 12th graders with the BNT162b2 Covid-19 vaccine, while 10th and 11th graders were not eligible.
  • - The study of 444,313 adolescents showed a low reporting rate of myocarditis/pericarditis: 1.8 cases per 100,000 after the first dose and 4.3 after the second dose.
  • - BNT162b2 vaccine effectiveness was high, at 91.1% after the first dose and 99.1% after the second dose, indicating it is safe and significantly reduces the risk of Covid-19 in teens.
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Background: Despite the extraordinary speed of mass vaccination efforts, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant in a vaccinee with coronavirus disease 2019 (COVID-19) mRNA vaccine was identified in an adult day service center (ADSC) of Jeju, South Korea. The primary objective of this study was to investigate the epidemiologic features in infection-vulnerable facilities with a high vaccination rate of BNT162b2 mRNA COVID-19 vaccine. The second was to estimate the secondary transmission prevention effect of the vaccine in the household members by vaccination status.

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Objectives: Pertussis or whooping cough-one of the most contagious diseases-is caused by the Gram-negative bacterium Bordetella pertussis. Despite a high vaccination rate, Korea recently experienced a resurgence of pertussis. This study explores patterns and possible explanations for this resurgence through an age-period-cohort analysis.

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  • - We created an infection matrix to study how COVID-19 spreads within households in Korea.
  • - Most infections in households occurred within the same age group rather than across different age groups.
  • - Adults were more likely to transmit the virus to children than the other way around.
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This study describes the epidemiological characteristics of coronavirus disease 2019 (COVID-19) based on reported cases from long-term care facilities. As of April 20, 2020, 3 long-term care facilities in a metropolitan area of South Korea had reported cases of COVID-19. These facilities' employees were presumed to be the sources of infection.

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We analyzed reports for 59,073 contacts of 5,706 coronavirus disease (COVID-19) index patients reported in South Korea during January 20-March 27, 2020. Of 10,592 household contacts, 11.8% had COVID-19.

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We describe the epidemiology of a coronavirus disease (COVID-19) outbreak in a call center in South Korea. We obtained information on demographic characteristics by using standardized epidemiologic investigation forms. We performed descriptive analyses and reported the results as frequencies and proportions for categoric variables.

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Background: As scientific findings of air pollution and subsequent health effects have been accumulating, public interest has also been growing. Accordingly, web visualization is suggested as an effective tool to facilitate public understanding in scientific evidence and to promote communication between the public and academia. We aimed to introduce an example of easy and effective web-based visualization of research findings, relying on predicted concentrations of particulate matter ≤ 10 µg/m (PM) and nitrogen dioxide (NO) obtained from our previous study in South Korea and Tableau software.

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  • - Pediatric allergic diseases like asthma, allergic rhinitis, and atopic eczema are linked to traffic-related air pollution (TRAP), with this study exploring the association using individual-level air pollution data from over 14,600 children in Seoul, Korea.
  • - The researchers calculated annual-average concentrations of pollutants like nitrogen oxide (NO) and particulate matter (PM) at each child's home and analyzed their relationship with allergic disease symptoms and diagnoses.
  • - Results indicated a significant association between atopic eczema symptoms and both NO and PM concentrations, suggesting that higher exposure to these pollutants increases the risk of developing this allergic disease.
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Although there has been suggestive evidence of the association between TRAP and ADs, findings remained inconsistent possibly due to limited population. We investigated the association between TRAP and ADs in a large population of children with rich spatial coverage and expanded age span in Seoul, Korea. TRAP exposures were estimated by categorized proximity to the nearest major road (≤150, 150-300, 300-500, and >500 m) and density of major roads within 300 meters from children's residences.

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Obesity is a global pandemic that brings about a myriad of health consequences. In the past, policies for combating obesity mainly focused on improving individual health and behavior, but nowadays some policies have changed and now concentrate on improving the built environment believing this can improve health through positive changes to health-related behaviors. We examined whether both individual and environmental factors were associated with body mass index in Seoul, the capital city of South Korea.

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Objectives: Cohort studies of associations between air pollution and health have used exposure prediction approaches to estimate individual-level concentrations. A common prediction method used in Korean cohort studies is ordinary kriging. In this study, performance of ordinary kriging models for long-term particulate matter less than or equal to 10 μm in diameter (PM10) concentrations in seven major Korean cities was investigated with a focus on spatial prediction ability.

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This study examined life expectancies in 25 gus, administrative districts of Seoul, the capital of Korea, by gender in 1995, 2002, and 2008 to explore trends in mortality inequality among areas. The authors constructed single-decrement life tables and employed between-group variance, the Theil index, and mean log deviation to measure absolute and relative disparities in life expectancy among areas during the periods 1995-2002 and 2002-2008. It was found that life expectancy gaps between gus have widened in absolute and relative terms in both genders over the decade, and that this pattern was particularly dramatic in females after 2002.

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