Publications by authors named "Seonhye Jang"
Article Synopsis
- Atopic dermatitis (AD) involves a Th2 inflammatory response damaging the skin, and there's a strong link between this condition and a specific strain of bacteria, A2-165, known for producing butyrate.
- Researchers have determined the 3D structure of an important enzyme, 3-hydroxybutyryl-CoA dehydrogenase (A2HBD), using advanced X-ray techniques, revealing its interactions with key molecules like acetoacetyl-CoA and NAD.
- The study highlights significant conformational changes in A2HBD when substrates bind, particularly noting how specific residues contribute to substrate recognition and the enzyme's overall catalytic activity.
Quantitative immunodiagnosis is one of the most commonly used methods for in vitro diagnostics. Various bioanalytical methods have been developed to quantitatively diagnose immune analytes; however, they require blood dilution pretreatment, reaction mixing, complicated experimental steps, and can cause diagnostic errors due to the hook effect. To address this issue, we introduced a simple immunoassay based on carbon nanoparticles (CNPs).
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