Enhanced dual-mode imaging: Superior photoacoustic and ultrasound endoscopy in live pigs using a transparent ultrasound transducer.

Dual-mode photoacoustic/ultrasound endoscopy (ePAUS) is a promising tool for preclinical and clinical interventions. To be clinically useful, ePAUS must deliver high-performance ultrasound imaging comparable to commercial systems and maintain high photoacoustic imaging performance at long working distances. This requires a transducer with an intact physical aperture and coaxial alignment of acoustic and optical beams within the probe, a challenging integration task.

Nonlinear beamforming for intracardiac echocardiography: a comparative study.

Unlabelled: Intracardiac echocardiography (ICE) enables cardiac imaging with a wide field of view, deep imaging depth, and high frame rate during surgery. However, strong sidelobe and grating lobe artifacts created by the ultra-compact transducer degrade its image quality, making diagnosis and monitoring of treatment difficult. Conventionally, aperture apodization algorithms are often used to suppress sidelobe and grating lobe artifacts at the expense of lateral resolution, which is undesirable in ICE.

An ultrasensitive and broadband transparent ultrasound transducer for ultrasound and photoacoustic imaging in-vivo.

Transparent ultrasound transducers (TUTs) can seamlessly integrate optical and ultrasound components, but acoustic impedance mismatch prohibits existing TUTs from being practical substitutes for conventional opaque ultrasound transducers. Here, we propose a transparent adhesive based on a silicon dioxide-epoxy composite to fabricate matching and backing layers with acoustic impedances of 7.5 and 4-6 MRayl, respectively.

X-ray free-electron laser induced acoustic microscopy (XFELAM).

The X-ray free-electron laser (XFEL) has remarkably advanced X-ray imaging technology and enabled important scientific achievements. The XFEL's extremely high power, short pulse width, low emittance, and high coherence make possible such diverse imaging techniques as absorption/emission spectroscopy, diffraction imaging, and scattering imaging. Here, we demonstrate a novel XFEL-based imaging modality that uses the X-ray induced acoustic (XA) effect, which we call X-ray free-electron laser induced acoustic microscopy (XFELAM).

Necking Reduction at Low Temperature in Aspect Ratio Etching of SiO at CF/H/Ar Plasma.

This study investigated the effect of temperature on the aspect-ratio etching of SiO in CF/H/Ar plasma using patterned samples of a 200 nm trench in a low-temperature reactive-ion etching system. Lower temperatures resulted in higher etch rates and aspect ratios for SiO. However, the plasma property was constant with the chuck temperature, indicated by the line intensity ratio from optical emission spectroscopy monitoring of the plasma.

Benefits of leaders' pleasurable recovery activities on follower performance via emotional contagion.

Recovery research has amply documented the benefits of employee recovery for their well-being and performance. However, most research to date has mainly focused on intraindividual benefits, so that we know relatively little about how focal employees' recovery activities might affect others at work. Bridging the gaps in the recovery and leadership literatures, this study focuses on leader-follower dyads and examines the interpersonal effects of leaders' recovery activities on followers' daily performance quality.

The influence of different hinge position on PTS during HTO: comparison between open-wedge and closed-wedge HTO.

Purpose: The purpose of this study was to determine the significance of hinge position through comparison between open-wedge and closed-wedge high tibial osteotomy (HTO) and to determine the ideal hinge position to minimize the effect of HTO on the posterior tibial slope (PTS) and medial proximal tibial angle (MPTA).

Methods: Procedures were performed on 32 cadaveric knees using open-wedge HTO with the standard hinge position or a low hinge position or closed-wedge HTO with the standard hinge position or a low hinge position. To define the standard hinge position in open wedge HTO, we drew a line 3-cm inferior to the medial tibial plateau toward the fibular head and located the intersection of this line with a longitudinal line 1-cm medial to fibular shaft.

Performance comparison of high-speed photoacoustic microscopy: opto-ultrasound combiner versus ring-shaped ultrasound transducer.

Photoacoustic microscopy (PAM) embedded with a 532 nm pulse laser is widely used to visualize the microvascular structures in both small animals and humans in vivo. An opto-ultrasound combiner (OUC) is often utilized in high-speed PAM to confocally align the optical and acoustic beams to improve the system's sensitivity. However, acoustic impedance mismatch in the OUC results in little improvement in the sensitivity.

Three-dimensional Multistructural Quantitative Photoacoustic and US Imaging of Human Feet in Vivo.

Background Monitoring the microcirculation in human feet is crucial in assessing peripheral vascular diseases, such as diabetic foot. However, conventional imaging modalities are more focused on diagnosis in major arteries, and there are limited methods to provide microvascular information in early stages of the disease. Purpose To investigate a three-dimensional (3D) noncontrast bimodal photoacoustic (PA)/US imaging system that visualizes the human foot morphologically and also reliably quantifies podiatric vascular parameters noninvasively.

Does a healthy lifestyle matter? A daily diary study of unhealthy eating at home and behavioral outcomes at work.

With abundant health-related information, the modern workforce is advised to engage in health-promoting behaviors such as good sleep, physical activities, and a healthy diet to stay productive at work. However, no study has provided a theoretical framework or empirical evidence on the association between employees' unhealthy eating behavior and the quality of their performance. Drawing from the stress and coping literature, the current study proposes a moderated mediation model to investigate the day-specific roles of (un)healthy lifestyle in regard to personal well-being and performance at work.

Prescription patterns of herbal medicine for menopausal disorders in major Korean medicine hospitals: a multicenter retrospective study.

Background: This study aimed to obtain the symptom, prescription and therapeutic patterns for the treatment of patients with menopausal syndrome in major Korean medicine (KM) hospitals.

Methods: We used a retrospective chart review of climacteric disorder and postmenopausal syndrome patients by examining medical records (ICD-10, menopausal and female climacteric states: N95.1, Menopausal and perimenopausal disorder, unspecified: N95.

Daily microbreaks in a self-regulatory resources lens: Perceived health climate as a contextual moderator via microbreak autonomy.

Grounded in self-regulatory resources and conservation of resources theories, the current research examines poor self-regulatory capacity as a precursor to microbreaks and their possible outcomes at work. Full-time employees completed multiple online surveys for 10 ( = 779 daily observations) and 5 workdays ( = 1,024 daily observations). In Study 1, multilevel path analysis results showed that on days when employees had poorer recovery at home (i.

12-Year longitudinal study linking within-person changes in work and family transitions and workplace injury risk.

Introduction: Despite the rich tradition of research on predictors of workplace injury, most studies rely on cross-sectional, between-person designs. Furthermore, prior research has often overlooked the possibility that factors outside the work domain can influence the occurrence of actual injuries at work. To address these limitations, the current study examined the effects of work and family demands on the occurrence of workplace injury.

Nonlinear pth root spectral magnitude scaling beamforming for clinical photoacoustic and ultrasound imaging.

A recently introduced nonlinear th root delay-and-sum (NL--DAS) beamforming (BF) technique for ultrasound (US) and photoacoustic (PA) imaging, achieving better spatial and contrast resolution compared to a conventional delay and sum (DAS) technique. While the method is advantageous for better resolution, it suffers from grainy speckles and dark areas in the image mainly due to the interference of non-sinusoidal functions. In this Letter, we introduce a modified NL--DAS technique called nonlinear th root spectral magnitude scaling (NL--SMS), which performs the th root on the spectral magnitude instead of the temporal amplitude.

Daily effects of continuous ICT demands on work-family conflict: Negative spillover and role conflict.

Growing concerns about intensive information and communication technology (ICT) use led to abundant research on its debilitating effects on employees' abilities to meet family demands. Drawing on the stressor-strain model, we conducted a daily diary study to investigate how different types of daily ICT demands experienced during work hours and after work influence work-family conflict (WFC) in the evening. We collected data from 98 full-time employees (793 day-level observations) for 10 consecutive workdays to understand employees' work-nonwork interface experiences, namely, negative spillover and role conflict.

An examination of the temporal order of helping behaviours and emotional exhaustion.

An emerging body of research has investigated the relationship between helping (as a type of organizational citizenship behaviour) and emotional exhaustion (as an aspect of employee health). Research has demonstrated a significant relationship between helping and emotional exhaustion, but the theoretical arguments for the causal direction vary across studies. Specifically, some researchers have conceptualized helping as an outcome of emotional exhaustion, while others have regarded helping as a predictor of emotional exhaustion.

3D PHOVIS: 3D photoacoustic visualization studio.

Photoacoustic (PA) imaging (or optoacoustic imaging) is a novel biomedical imaging method in biological and medical research. This modality performs morphological, functional, and molecular imaging with and without labels in both microscopic and deep tissue imaging domains. A variety of innovations have enhanced 3D PA imaging performance and thus has opened new opportunities in preclinical and clinical imaging.

Super Wide-Field Photoacoustic Microscopy of Animals and Humans In Vivo.

Acoustic-resolution photoacoustic micro-scopy (AR-PAM) is an emerging biomedical imaging modality that combines superior optical sensitivity and fine ultrasonic resolution in an optical quasi-diffusive regime (~1-3 mm in tissues). AR-PAM has been explored for anatomical, functional, and molecular information in biological tissues. Heretofore, AR-PAM systems have suffered from a limited field-of-view (FOV) and/or slow imaging speed, which have precluded them from routine preclinical and clinical applications.

How to benefit from weekend physical activities: Moderating roles of psychological recovery experiences and sleep.

This study examines the short-term recovery benefits of weekend physical activity on reduced negative affective state (NA) on Monday morning, using a weekly diary method from 70 employees across four weekends (repeated pre- and post-weekend measures). The first hypothesis tests the within-person relationship between weekend physical activity and post-weekend NA. The results of multilevel path analysis show that the main effect of weekend physical activity on reduced Monday NA is not significant.

High-Contrast Imaging of Cholesterol Crystals in Rabbit Arteries Ex Vivo Using LED-Based Polarization Microscopy.

Detection of cholesterol crystals (Chcs) in atherosclerosis disease is important for understanding the pathophysiology of atherosclerosis. Polarization microscopy (PM) has been in use traditionally for detecting Chcs, but they have difficulty in distinguishing Chcs with other crystalline materials in tissue, such as collagens. Thus, most studies using PM have been limited to studying cell-level samples.

A Review of the Literature on Culture-Negative Periprosthetic Joint Infection: Epidemiology, Diagnosis and Treatment.

Purpose: The prevalence of periprosthetic joint infection (PJI) has increased with the increasing incidence of arthroplasty surgery. Considering identification of causative microorganisms is crucial for treatment of PJI, culture-negative (CN) PJI is a significant clinical issue. The purpose of the present study is to describe epidemiology, diagnosis and treatment of CN PJI based on review of the literature to help prevent delayed diagnosis and improve clinical outcomes of CN PJI.

An investigation of emotional intelligence measures using item response theory.

This study investigated the psychometric properties of 3 frequently administered emotional intelligence (EI) scales (Wong and Law Emotional Intelligence Scale [WLEIS], Schutte Self-Report Emotional Intelligence Test [SEIT], and Trait Emotional Intelligence Questionnaire [TEIQue]), which were developed on the basis of different theoretical frameworks (i.e., ability EI and mixed EI).

2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists.

A series of 2-alkyl/alkenyl pyridine C-region derivatives of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides were investigated as hTRPV1 antagonists. Multiple compounds showed excellent and stereospecific TRPV1 antagonism with better potency than previous lead 2. Among them, compound 15f demonstrated a strong analgesic profile in a rat neuropathic pain model and blocked capsaicin-induced hypothermia in a dose-dependent manner.