Laparoscopic excision and repair of a cesarean scar pregnancy in a woman with uterine didelphys: a case report.

Cesarean scar pregnancy (CSP) is a rare complication that occurs in less than 1% of ectopic pregnancies, and uterine didelphys is one of the rarest uterine forms. We report a successful laparoscopic excision and repair of CSP in a woman with uterine didelphys and a double vagina. A 34-year-old gravida one, para one woman with a history of low transverse cesarean section presented to our hospital with a suspected CSP.

Loss of YY1 expression predicts unfavorable prognosis in stage III colorectal cancer.

Background: Yin Yang 1 (YY1), the multifunctional transcription factor, has recently been assigned biological properties related to human malignancies. YY1 can facilitate both tumor suppression and tumor growth. The conflicting role of YY1 in human malignancies is not yet fully explained.

The clinicopathologic significance of extranodal tumor extension in locally advanced (pT3) colorectal adenocarcinoma and its association with the loss of E-cadherin expression.

We investigated the clinicopathologic significance of extranodal tumor extension (ENTE) in locally advanced and prognostically inhomogeneous pT3 (pathologic T3) colorectal adenocarcinomas with regional lymph node metastasis. ENTE is defined as an interruption of the nodal capsule by tumor cells with extranodal growth. ENTE was observed in 46.

Low Expression of Single-stranded DNA Binding Protein 2 (SSBP2) Predicts Unfavourable Postoperative Outcomes in Patients With Clear Cell Renal Cell Carcinoma.

Background: Single-stranded DNA binding protein 2 (SSBP2) is a subunit of a single-stranded DNA binding complex, which is involved in the maintenance of hematopoietic stem cells and stress responses. Numerous studies have suggested that SSBP2 functions as a tumor suppressor and is silenced through a pathway mediated by promoter hypermethylation. However, the role of SSBP2 in human renal cell carcinoma has not been reported, to date.

N-Containing 1,7-Octadiyne Derivatives for Living Cyclopolymerization Using Grubbs Catalysts.

Synthesis of a new class of conjugated polyenes containing N-heterocyclic six-membered rings was demonstrated via cyclopolymerization of N-containing 1,7-octadiyne derivatives using Grubbs catalysts. Successful cyclopolymerization was achieved by introducing protecting groups to the amines in the monomers. Moreover, a hydrazide-type monomer containing a di--butyloxycarbonyl group () promoted the living cyclopolymerization to give poly() with a controlled molecular weight and narrow dispersity.

Expression of aldehyde dehydrogenase 6 reduces inhibitory effect of furan derivatives on cell growth and ethanol production in Saccharomyces cerevisiae.

Yeast dehydrogenases and reductases were overexpressed in Saccharomyces cerevisiae D452-2 to detoxify 2-furaldehyde (furfural) and 5-hydroxymethyl furaldehyde (HMF), two potent toxic chemicals present in acid-hydrolyzed cellulosic biomass, and hence improve cell growth and ethanol production. Among those enzymes, aldehyde dehydrogenase 6 (ALD6) played the dual roles of direct oxidation of furan derivatives and supply of NADPH cofactor to their reduction reactions. Batch fermentation of S.