Correlations between renal function and the total kidney volume measured on imaging for autosomal dominant polycystic kidney disease: A systematic review and meta-analysis.

Purpose: To provide a systematic summary of total kidney volume (TKV) as an imaging biomarker in clinical trials for autosomal dominant polycystic kidney disease (ADPKD), focusing on the correlation between TKV and renal function.

Methods: A computerized literature search was performed using MEDLINE and EMBASE databases for studies that evaluated the correlation between TKV and the glomerular filtration rate (GFR) and between the TKV growth rate and GFR decline rate. A meta-analysis was performed to generate the summary correlation coefficient (r).

HASTE sequence with parallel acquisition and T2 decay compensation: application to carotid artery imaging.

T2-weighted carotid artery images acquired using the turbo spin-echo (TSE) sequence frequently suffer from motion artifacts due to respiration and blood pulsation. The possibility of using HASTE sequence to achieve motion-free carotid images was investigated. The HASTE sequence suffers from severe blurring artifacts due to signal loss in later echoes due to T2 decay.