Publications by authors named "Seong Woo Cho"

Article Synopsis
  • TOX is a transcription factor linked to T cell exhaustion during chronic infections, but its role in inflammation, particularly during COVID-19, is not well understood.
  • The study found that TOX promotes severe inflammation by binding to the RAGE receptor during SARS-CoV-2 infection, leading to critical lung issues like acute respiratory distress syndrome (ARDS).
  • Interventions that block TOX or disable RAGE showed potential in reducing harmful effects, suggesting that targeting the TOX-RAGE pathway could be a promising strategy for treating severe pulmonary infections.
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Background: Interstitial lung abnormality (ILA) is closely related to lung cancer. This study aimed to assess whether the presence of ILA is associated with the clinicoradiological features of elderly patients (≥70 years) with early-stage non-small cell lung cancer (NSCLC).

Methods: Elderly patients who underwent surgical resection for stage I or II NSCLC with preserved lung function between 2012 and 2019 were retrospectively identified.

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PTR2 in Arabidopsis thaliana is negatively regulated by ABI4 and plays a key role in water uptake by seeds, ensuring that imbibed seeds proceed to germination. Peptide transporters (PTRs) transport nitrogen-containing substrates in a proton-dependent manner. Among the six PTRs in Arabidopsis thaliana, the physiological role of the tonoplast-localized, seed embryo abundant PTR2 is unknown.

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This study was conducted to identify the influence of flour characteristics of 13 Korean wheat cultivars on quality attributes of pancake. Pancake diameter showed negative correlation with SRC with distilled water and pancake height and positive correlation with springiness of cooked pancake. Springiness of baked pancake was under negative correlation with protein content, SDSS, dry gluten content, and positive correlation with final viscosity and setback in pasting properties of flour.

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We describe the case of a patient with an acute subdural hematoma (SDH) that was removed using urokinase irrigation after burr hole trephination in a limited situation where craniotomy was not possible. A 90-year-old woman was admitted to our hospital with a stuporous mental status. Computed tomography (CT) scans revealed a chronic SDH, and a burr hole procedure was performed.

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Developing wheat-alien chromosome introgression lines to improve bread wheat's resistance to stresses, such as drought, salinity stress and diseases, requires reliable markers to identify and characterize the alien chromatins. Leymus mollis is a wild relative of bread wheat resistant to salinity and economically important diseases of wheat, but its genome sequence and cytological markers are not available. We devised a molecular marker-assisted strategy for L.

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Unlabelled: Vascular networks are the first sites exposed to cationic polymer nanoparticles (NPs) administered intravenously, and thus function as a barrier for NPs reaching the target organ. While cationic polymer NPs have been intensively studied as non-viral delivery systems, their biological effects in human microvessels have been poorly investigated due to a lack of appropriate in vitro systems. Here, we employed a three-dimensional microvessel on a chip, which accurately models in vivo conditions.

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Objective: We aimed to investigate the current diagnostic incidence, and medical and psychiatric comorbidities of reactive attachment disorder (RAD) using the National Health Insurance Review and Assessment (HIRA) claims data.

Methods: To examine the diagnostic incidence, we selected patients who were under 10-year-old and who had at least one medical claim containing a 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) code for RAD (F94.1 and F94.

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Copper (Cu) is a important micronutrient for plants, but it is extremely toxic to plants at high concentration and can inactivate and disturb protein structures. To explore the Cu stress-induced tolerance mechanism, the present study was conducted on the roots of sorghum seedlings exposed to 50 and 100 µM CuSO for 5 days. Accumulation of Cu increased in roots when the seedlings were treated with the highest concentration of Cu ions (100 μM).

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Children with autism are often medicated to manage emotional and behavioral symptoms; yet, data on such pharmacotherapy is insufficient. In this study, we investigated the Korean National Health Insurance Claims Database (NHICD) information related to autism incidence and psychotropic medication use. From the 2010-2012 NHICD, we selected a total of 31,919,732 subjects under 19 years old.

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Chromosome engineering is an important approach for generating wheat germplasm. Efficient development of chromosome aberrations will facilitate the introgression and application of alien genes in wheat. In this study, zebularine, a DNA methylation transferase inhibitor, was successfully used to induce chromosome aberrations in the octoploid triticale cultivar Jinghui#1.

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Copper (Cu) is an essential micronutrient required for normal growth and development of plants; however, at elevated concentrations in soil, copper is also generally considered to be one of the most toxic metals to plant cells due to its inhibitory effects against many physiological and biochemical processes. In spite of its potential physiological and economical significance, molecular mechanisms under Cu stress has so far been grossly overlooked in sorghum. To explore the molecular alterations that occur in response to copper stress, the present study was performed in ten-day-old Cu-exposed leaves of sorghum seedlings.

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Cadmium (Cd) stress may cause serious morphological and physiological abnormalities in addition to altering the proteome in plants. The present study was performed to explore Cd-induced morpho-physiological alterations and their potential associated mechanisms in Sorghum bicolor leaves at the protein level. Ten-day-old sorghum seedlings were exposed to different concentrations (0, 100, and 150 μM) of CdCl2, and different morpho-physiological responses were recorded.

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Mitochondria are important organelles for cellular respiration within the eukaryotic cell and have many important functions including vitamin synthesis, amino acid metabolism and photorespiration. To investigate the mitochondrial proteome of the roots of wheat seedlings, a systematic and targeted analysis were carried out on the mitochondrial proteome from 15 day-old wheat seedling root material. Mitochondria were isolated by Percoll gradient centrifugation; and extracted proteins were disassociated and analyzed by Tricine SDS-PAGE couple to LTQ-FTICR mass spectrometry.

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Gametophytic factors mediate pollen-pistil interactions in maize ( L.) and play active roles in limiting gene flow among maize populations and between maize and teosinte. This study was carried out to identify proteins and investigate the mechanism of gametophytic factors using protein analysis.

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The root apex is considered the first sites of aluminum (Al) toxicity and the reduction in root biomass leads to poor uptake of water and nutrients. Aluminum is considered the most limiting factor for plant productivity in acidic soils. Aluminum is a light metal that makes up 7 % of the earth's scab dissolving ionic forms.

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The generation of multiple vortex cones using an annular aperture array and a spatial light modulator (SLM) is studied. The direct downscale imaging of an SLM on the surface of an annular aperture enables the direct-phase modulation of the annular aperture. It is experimentally demonstrated that the direct-phase modulation of an annular aperture array can control both the topological charge and the horizontal positions of multiple vortex cones simultaneously.

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The prevalence of intervertebral disc herniation (IDH) of the thoracic spine is rare compared to the cervical or lumbar spine. In particular, IDH of the upper thoracic spine is extremely rare. We report the case of T1-2 IDH and its treatment, with a literature review.

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Leaves are the final site of salinity perception through the roots. To better understand how wheat chloroplasts proteins respond to salt stress, the study aimed to the physiochemical and comparative proteomics analysis. Seedlings (12-days-old) were exposed to 150 mM NaCl for 1, 2, or 3 days.

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We present that two distinct optical properties of light, the spin angular momentum (SAM) and the orbital angular momentum (OAM), can be coupled in the plasmonic vortex. If a plasmonic vortex lens (PVL) is illuminated by the helical vector beam (HVB) with the SAM and OAM, then those distinct angular momenta contribute to the generation of the plasmonic vortex together. The analytical model reveals that the total topological charge of the generated plasmonic vortex is given by a linear summation of those of the SAM and OAM, as well as the geometric charge of the PVL.

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The generation of surface plasmon vortices with arbitrary higher order vortex topological charges with novel plasmonic vortex lens is experimentally demonstrated. It is shown that the polarization sensitivity of the plasmonic vortex lens can be utilized for the dynamic switching of the surface plasmon vortices with different topological charges. A simple algebraic rule related to the vortex topological charge change in the dynamic switching is formulated, and its proof is provided with theory and experiment.

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Phase-shifting interferometry with a genetic algorithm is proposed. The correction of unknown phase-shifting error is an important task in general phase-shifting interferometry. Since phase-shifting errors generate twin image noise in a reconstructed image, we can reduce the phase-shifting errors indirectly by trying to eliminate the twin-image noise in the reconstructed image.

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A display system that simultaneously displays two-dimensional (2D) and three-dimensional (3D) images using a pinhole array on a liquid crystal (LC) panel is proposed. Using the transparent structure of the LC panel, the system can generate or eliminate pinholes electrically and can display a 3D image in a selectable specific area of the display panel, while 2D images are displayed on the rest of the screen. An analysis showing the advantages and limitations of the proposed system is provided.

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A novel approach to an integral imaging system using a pliable plastic optical fiber array is proposed. The proposed system has the advantage that it can utilize a light source for three-dimensional (3D) images at an arbitrary location because the point light sources are formed by the plastic fiber array with flexible optical paths. Two-dimensional images can also be expressed in the proposed system.

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A depth-enhanced three-dimensional integral imaging system with electrically variable image planes is proposed. For implementing the variable image planes, polymer-dispersed liquid-crystal (PDLC) films and a projector are adopted as a new display system in the integral imaging. Since the transparencies of PDLC films are electrically controllable, we can make each film diffuse the projected light successively with a different depth from the lens array.

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