Publications by authors named "Seong Hyun Yang"
Exosomes released from skeletal muscle cells play important roles in myogenesis and muscle development via the transfer of specific signal molecules. In this study, we investigated whether exosomes secreted during myotube differentiation from human skeletal myoblasts (HSkM) could induce a cellular response from human adipose-derived stem cells (HASCs) and enhance muscle regeneration in a muscle laceration mouse model. The exosomes contained various signal molecules including myogenic growth factors related to muscle development, such as insulin-like growth factors (IGFs), hepatocyte growth factor (HGF), fibroblast growth factor-2 (FGF2), and platelet-derived growth factor-AA (PDGF-AA).
View Article and Find Full Text PDFTwo novel bacterial strains, GH2-4T and GH2-5, were isolated from mangrove soil near the seashore of Weno island in Chuuk state, Micronesia, and were characterized by a polyphasic approach. The two strains were strictly aerobic, Gram-staining-positive, motile, endospore-forming rods that were catalase- and oxidase-positive. Colonies were circular, convex, stringy and transparent yellowish (GH2-4T) or opaque whitish (GH2-5).
View Article and Find Full Text PDFArticle Synopsis
- A new Gram-negative, aerobic bacterium called MEBiC06554(T) was isolated from seawater in the East Sea of Korea and identified as a distinct member of the Kordiimonadales order.
- Genetic analysis showed that it is closely related to Kordiimonas gwangyangensis but forms its own unique lineage.
- Growth conditions were determined, revealing optimal growth at 20°C, pH 7, and 3-3.5% NaCl, leading to the classification of MEBiC06554(T) as a new species, Kordiimonas aquimaris sp. nov.